Figure 1

Identified molecular mechanisms for alcohol-induced endoplasmic reticulum stress and hepatic injuries. See the context for details.
Figure 2

Proposed model depicts novel endoplasmic reticulum (ER) stress mechanisms linking alcohol (EtOH) and/or high-fat diet (HFD), cyclin D, ERAD, estrogen receptor α (ERα) variants, FOXO3, and Shp with hepatocellular carcinogenesis (HCC). Solid lines represent established pathways based on the literature; dashed lines represent emerging mechanisms under investigations. See the context for details.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int J Hepatol
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