FIGURE SUMMARY
Title

Rheotaxis in larval zebrafish is mediated by lateral line mechanosensory hair cells

Authors
Suli, A., Watson, G.M., Rubel, E.W., and Raible, D.W.
Source
Full text @ PLoS One
Fig. 3

Rheotaxis depends on level of hair cell impairment or damage and is restored during regeneration.

A) Mechanotransduction, as shown by FM1–43 dye uptake, is blocked when tip-links are broken at ~30 min after EDTA treatment (acute) and is restored again at 4–5 hours post treatment (recovery) (flow = 0.16 cm/s). B) Rheotaxis is impaired acutely after EDTA treatment and restored to control levels after recovery (n = 5). C) Ablating the lateral line input by different neomycin doses leads to a dose dependent rheotaxis impairment (n = 6) (flow = 0.14 cm/s). D) Rheotaxis is restored during mechanosensory hair cell regeneration (n = 5) (flow = 0.16 cm/s). Statistics: C) Statistics: ANOVA with Tukey post-tests. B,D) Paired t-test. Error bars show standard deviation. * p = 0.01–0.05, ** p = 0.01–0.001, *** p<0.001.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One
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