FIGURE SUMMARY
Title

Zebrafish bioassay-guided natural product discovery: isolation of angiogenesis inhibitors from East african medicinal plants

Authors
Crawford, A.D., Liekens, S., Kamuhabwa, A.R., Maes, J., Munck, S., Busson, R., Rozenski, J., Esguerra, C.V., and de Witte, P.A.
Source
Full text @ PLoS One
Fig. 1

Crude methanolic extracts and isolated compounds inhibit vascular outgrowth in fli-1:EGFP transgenic embryos.

All embryos are 40 hpf, with anterior to the left, scale bar = 100 μm. a, b, DMSO-treated control; c, embryo treated with 200 μg/ml O. sinuatum extract; d, embryo treated with 10 μg/ml P. barbatus extract; e, embryo treated with 8 μM emodin; f, embryo treated with 2 μM coleon AL.
Fig. 4

Emodin and coleon AL inhibit endothelial cell migration in vitro.

a, control (immediate); b, control; c, 30 μM emodin; d, 30 μM coleon AL.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One
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