FIGURE SUMMARY
Title

The BMP pathway acts to directly regulate Tbx20 in the developing heart

Authors
Mandel, E.M., Kaltenbrun, E., Callis, T.E., Zeng, X.X., Marques, S.R., Yelon, D., Wang, D.Z., and Conlon, F.L.
Source
Full text @ Development
Fig. 8

The Xenopus Tbx20 334 bp cardiac regulatory element drives EGFP expression in a cardiac-specific manner in zebrafish. (A,B) In situ hybridization depicts expression of Tbx20 in wild-type zebrafish embryos and alk8sk42 (Marques and Yelon, 2009) mutant siblings at the 10-somite stage; dorsal views, anterior to the top. Tbx20 expression is reduced in both the anterior lateral plate mesoderm, including the bilateral cardiac primordia, and the midline mesenchyme of zygotic alk8 mutants. (C-E) Lateral views of a live zebrafish embryo at 48 hpf, following injection with the XTbx20(–334)-EGFP transgene. Injected embryos express EGFP in the myocardium (arrows).

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development
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