ZFIN Person: Her, Guor Muor

ZFIN ID: ZDB-PERS-990303-27

ZFIN ID: ZDB-PERS-990303-27

Her, Guor Muor

Email:	gmher@nycu.edu.tw
URL:
Affiliation:	Her Lab
Address:	Institute of Biopharmaceutical Sciences, National Yang-Ming University No.155, Sec.2, Linong Street, Taipei, 112 Taiwan (ROC)
Country:	Taiwan
Phone:	+886-2-2826-7990
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Lin, C.Y., Yeh, K.Y., Lai, H.H., Her, G.M. (2023) AgRP Neuron-Specific Ablation Represses Appetite, Energy Intake, and Somatic Growth in Larval Zebrafish. Biomedicines. 11(2):

Lai, H.H., Yeh, K.Y., Hsu, H.M., Her, G.M. (2022) Deficiency of Adipose Triglyceride Lipase Induces Metabolic Syndrome and Cardiomyopathy in Zebrafish. International Journal of Molecular Sciences. 24(1):

Tsai, Y.W., Jeng, K.S., He, M.K., Hsieh, Y.W., Lai, H.H., Lai, C.Y., Huang, C.C., Chang, C.F., Huang, C.T., Her, G.M. (2021) MXD3 Promotes Obesity and the Androgen Receptor Signaling Pathway in Gender-Disparity Hepatocarcinogenesis. Cells. 10(12):

Lai, C.Y., Yeh, K.Y., Liu, B.F., Chang, T.M., Chang, C.H., Liao, Y.F., Liu, Y.W., Her, G.M. (2021) MicroRNA-21 Plays Multiple Oncometabolic Roles in Colitis-Associated Carcinoma and Colorectal Cancer via the PI3K/AKT, STAT3, and PDCD4/TNF-α Signaling Pathways in Zebrafish. Cancers. 13(21):

Hsieh, Y.W., Tsai, Y.W., Lai, H.H., Lai, C.Y., Lin, C.Y., Her, G.M. (2021) Depletion of Alpha-Melanocyte-Stimulating Hormone Induces Insatiable Appetite and Gains in Energy Reserves and Body Weight in Zebrafish. Biomedicines. 9(8):

Lai, C.Y., Yeh, K.Y., Lin, C.Y., Hsieh, Y.W., Lai, H.H., Chen, J.R., Hsu, C.C., Her, G.M. (2021) MicroRNA-21 Plays Multiple Oncometabolic Roles in the Process of NAFLD-Related Hepatocellular Carcinoma via PI3K/AKT, TGF-β, and STAT3 Signaling. Cancers. 13(5):

Lai, C.Y., Lin, C.Y., Hsu, C.C., Yeh, K.Y., Her, G.M. (2018) Liver-directed microRNA-7a depletion induces nonalcoholic fatty liver disease by stabilizing YY1-mediated lipogenic pathways in zebrafish. Biochimica et biophysica acta. 1863(8):844-856

Hsu, C.C., Lai, C.Y., Lin, C.Y., Yeh, K.Y., Her, G.M. (2017) MicroRNA-27b Depletion Enhances Endotrophic and Intravascular Lipid Accumulation and Induces Adipocyte Hyperplasia in Zebrafish. International Journal of Molecular Sciences. 19(1)

Yeh, K.Y., Lai, C.Y., Lin, C.Y., Hsu, C.C., Lo, C.P., Her, G.M. (2017) ATF4 overexpression induces early onset of hyperlipidaemia and hepatic steatosis and enhances adipogenesis in zebrafish. Scientific Reports. 7:16362

Wang, B.J., Her, G.M., Hu, M.K., Chen, Y.W., Tung, Y.T., Wu, P.Y., Hsu, W.M., Lee, H., Jin, L.W., Hwang, S.L., Chen, R.P., Huang, C.J., Liao, Y.F. (2017) ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 114(15):E3129-E3138

Roy, P., Periasamy, A.P., Lin, C., Her, G., Chiu, W., Li, C., Shu, C., Huang, C., Liang, C., Chang, H. (2015) Photoluminescent graphene quantum dots for in vivo imaging of apoptotic cells. Nanoscale. 7(6):2504-10

Tung, Y.T., Wang, B.J., Hsu, W.M., Hu, M.K., Her, G.M., Huang, W.P., and Liao, Y.F. (2014) Presenilin-1 regulates the expression of p62 to Govern p62-dependent Tau degradation. Molecular neurobiology. 49(1):10-27

Pai, W.Y., Hsu, C.C., Lai, C.Y., Chang, T.Z., Tsai, Y.L., and Her, G.M. (2013) Cannabinoid receptor 1 promotes hepatic lipid accumulation and lipotoxicity through the induction of SREBP-1c expression in zebrafish. Transgenic Research. 22(4):823-38

Her, G.M., Pai, W.Y., Lai, C.Y., Hsieh, Y.W., and Pang, H.W. (2013) Ubiquitous transcription factor YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 expression. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1831(6):1037-51

Hsu, C.C., Pai, W.Y., Lai, C.Y., Lu, M.W., and Her, G.M. (2013) Genetic characterization and in vivo image analysis of novel zebrafish Danio rerio pigment mutants. Journal of Fish Biology. 82(5):1671-1683

Lee, S.H., Peng, K.C., Lee, L.H., Pan, C.Y., Hour, A.L., Her, G.M., Hui, C.F., and Chen, J.Y. (2013) Characterization of tilapia (Oreochromis niloticus) viperin expression, and inhibition of bacterial growth and modulation of immune-related gene expression by electrotransfer of viperin DNA into zebrafish muscle. Veterinary Immunology and Immunopathology. 151(3-4):217-228

Her, G.M., Hsu, C.C., Hong, J.R., Lai, C.Y., Hsu, M.C., Pang, H.W., Chan, S.K., and Pai, W.Y. (2011) Overexpression of gankyrin induces liver steatosis in zebrafish (Danio rerio). Biochimica et biophysica acta. Molecular and cell biology of lipids. 1811(9):536-48

Chang, C.W., Su, Y.C., Her, G.M., Ken, C.F., and Hong, J.R. (2011) Betanodavirus induces oxidative stress-mediated cell death that prevented by anti-oxidants and zfcatalase in fish cells. PLoS One. 6(10):e25853

Zhan, H., Spitsbergen, J.M., Qing, W., Wu, Y.L., Paul, T.A., Casey, J.W., Her, G.M., and Gong, Z. (2010) Transgenic Expression of Walleye Dermal Sarcoma Virus rv-cyclin Gene in Zebrafish and Its Suppressive Effect on Liver Tumor Development After Carcinogen Treatment. Marine biotechnology (New York, N.Y.). 12(6):640-649

Hsu, C.C., Hou, M.F., Hong, J.R., Wu, J.L., and Her, G.M. (2010) Inducible Male Infertility by Targeted Cell Ablation in Zebrafish Testis. Marine biotechnology (New York, N.Y.). 12(4):466-478

Shieh, Y.S., Chang, Y.S., Hong, J.R., Chen, L.J., Jou, L.K., Hsu, C.C., and Her, G.M. (2010) Increase of hepatic fat accumulation by liver specific expression of Hepatitis B virus X protein in zebrafish. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1801(7):721-730

Chiu, C.L., Wu, J.L., Her, G.M., Chou, Y.L., and Hong, J.R. (2010) Aquatic birnavirus capsid protein, VP3, induces apoptosis via the Bad-mediated mitochondria pathway in fish and mouse cells. Apoptosis : an international journal on programmed cell death. 15(6):653-668

Chen, L.J., Hsu, C.C., Hong, J.R., Jou, L.K., Tseng, H.C., Wu, J.L., Liou, Y.C., and Her, G.M. (2008) Liver-specific expression of p53-negative regulator mdm2 leads to growth retardation and fragile liver in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(4):1070-1081

Rekha, R.D., Amali, A.A., Her, G.M., Yeh, Y.H., Gong, H.Y., Hu, S.Y., Lin, G.H., and Wu, J.L. (2008) Thioacetamide accelerates steatohepatitis, cirrhosis and HCC by expressing HCV core protein in transgenic zebrafish Danio rerio. Toxicology. 243(1-2):11-22

Amali, A.A., Rekha, R.D., Lin, C.J., Wang, W.L., Gong, H.Y., Her, G.M., and Wu, J.L. (2006) Thioacetamide induced liver damage in zebrafish embryo as a disease model for steatohepatitis. Journal of Biomedical Science. 13(2):225-232

Her, G.M., Cheng, C.H., Hon, J.R., Sundaram, G.S., and Wu, J.L. (2006) Imbalance in liver homeostasis leading to hyperplasia by overexpressing either one of the Bcl-2-related genes, zfBLP1 and zfMcl-1a. Developmental Dynamics : an official publication of the American Association of Anatomists. 235(2):515-523

Her, G.M., Yeh, Y.H., and Wu, J.L. (2004) Functional conserved elements mediate intestinal-type fatty acid binding protein (I-FABP) expression in the gut epithelia of zebrafish larvae. Developmental Dynamics : an official publication of the American Association of Anatomists. 230(4):734-742

Amali, A.A., Lin, C.J., Chen, Y.H., Wang, W.L., Gong, H.Y., Lee, C.Y., Ko, Y.L., Lu, J.K., Her, G.M., Chen, T.T., and Wu, J.L. (2004) Up-regulation of muscle-specific transcription factors during embryonic somitogenesis of zebrafish (Danio rerio) by knock-down of myostatin-1. Developmental Dynamics : an official publication of the American Association of Anatomists. 229(4):847-856

Her, G.M., Chiang, C.C., and Wu, J.L. (2004) Zebrafish intestinal fatty acid binding protein (I-FABP) gene promoter drives gut-specific expression in stable transgenic fish. Genesis (New York, N.Y. : 2000). 38(1):26-31

Her, G.M., Yeh, Y-.H., and Wu, J.-L. (2003) 435-bp liver regulatory sequence in the liver fatty acid binding protein (L-FABP) gene is sufficient to modulate liver regional expression in transgenic zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 227(3):347-356

Her, G.-M., Chiang, C.-C., Chen, W.-Y., and Wu, J.-L. (2003) In vivo studies of liver-type fatty acid binding protein (L-FABP) gene expression in liver of transgenic zebrafish (Danio rerio). FEBS letters. 538(1-3):125-133

NON-ZEBRAFISH PUBLICATIONS