ZFIN ID: ZDB-PERS-180131-1
Paatero, Ilkka
Email: ilanpa@utu.fi
URL: http://www.btk.fi/zebrafish
Affiliation: Ivaska lab
and also: Zebrafish Core
Address: Zebrafish Core Turku Centre for Biotechnology University of Turku and Åbo Akademi University Tykistokatu 6B 20520 Turku Finland
Country: Finland
Phone: +358 29 450 3789
Fax:
ORCID ID: 0000-0001-5926-2396


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Al-Akhrass, H., Conway, J.R.W., Poulsen, A.S.A., Paatero, I., Kaivola, J., Padzik, A., Andersen, O.M., Ivaska, J. (2021) A feed-forward loop between SorLA and HER3 determines heregulin response and neratinib resistance. Oncogene. 40(7):1300-1317
Heliste, J., Chheda, H., Paatero, I., Salminen, T.A., Akimov, Y., Paavola, J., Elenius, K., Aittokallio, T. (2019) Genetic and functional implications of an exonic TRIM55 variant in heart failure. Journal of Molecular and Cellular Cardiology. 138:222-233
Sahgal, P., Alanko, J., Icha, J., Paatero, I., Hamidi, H., Arjonen, A., Pietilä, M., Rokka, A., Ivaska, J. (2019) GGA2 and RAB13 promote activity-dependent β1-integrin recycling. Journal of Cell Science. 132(11):
Paatero, I., Veikkolainen, V., Mäenpää, M., Schmelzer, E., Belting, H.G., Pelliniemi, L.J., Elenius, K. (2018) ErbB4 tyrosine kinase inhibition impairs neuromuscular development in zebrafish embryos. Molecular biology of the cell. 30(2):209-218
Paatero, I., Sauteur, L., Lee, M., Lagendijk, A.K., Heutschi, D., Wiesner, C., Guzmán, C., Bieli, D., Hogan, B.M., Affolter, M., Belting, H.G. (2018) Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin-F-actin based oscillatory cell-cell interaction. Nature communications. 9:3545
Pekkonen, P., Alve, S., Balistreri, G., Gramolelli, S., Tatti-Bugaeva, O., Paatero, I., Niiranen, O., Tuohinto, K., Perälä, N., Taiwo, A., Zinovkina, N., Repo, P., Icay, K., Ivaska, J., Saharinen, P., Hautaniemi, S., Lehti, K., Ojala, P.M. (2018) Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation. eLIFE. 7
Jacquemet, G., Paatero, I., Carisey, A.F., Padzik, A., Orange, J.S., Hamidi, H., Ivaska, J. (2017) FiloQuant reveals increased filopodia density during breast cancer progression. The Journal of cell biology. 216:3387-3403

NON-ZEBRAFISH PUBLICATIONS
Paatero I, Seagroves TN, Vaparanta K, Han W, Jones FE, Johnson RS, Elenius K.Hypoxia-inducible factor-1α induces ErbB4 signaling in the differentiating mammary gland.J Biol Chem. 2014 Aug 8;289(32):22459-69. doi: 10.1074/jbc.M113.533497.
Paatero I, Lassus H, Junttila TT, Kaskinen M, Bützow R, Elenius K.CYT-1 isoform of ErbB4 is an independent prognostic factor in serous ovarian cancer and selectively promotes ovarian cancer cell growth in vitro.Gynecol Oncol. 2013 Apr;129(1):179-87. doi: 10.1016/j.ygyno.2012.12.044.
Paatero I, Jokilammi A, Heikkinen PT, Iljin K, Kallioniemi OP, Jones FE, Jaakkola PM, Elenius K.Interaction with ErbB4 promotes hypoxia-inducible factor-1α signaling.J Biol Chem. 2012 Mar 23;287(13):9659-71. doi: 10.1074/jbc.M111.299537.
Joensuu K, Paatero I, Alm JJ, Elenius K, Aro HT, Heino TJ, Hentunen TA.Interaction between marrow-derived human mesenchymal stem cells and peripheral blood mononuclear cells in endothelial cell differentiation.Scand J Surg. 2011;100(3):216-22.
Paatero I, Elenius K.ErbB4 and its isoforms: patentable drug targets?Recent Pat DNA Gene Seq. 2008;2(1):27-33
Sundvall M, Korhonen A, Paatero I, Gaudio E, Melino G, Croce CM, Aqeilan RI, Elenius K.Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms.Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4162-7. doi: 10.1073/pnas.0708333105.
Iivanainen E, Paatero I, Heikkinen SM, Junttila TT, Cao R, Klint P, Jaakkola PM, Cao Y, Elenius K.Intra- and extracellular signaling by endothelial neuregulin-1.Exp Cell Res. 2007 Aug 1;313(13):2896-909.
Sundvall M, Peri L, Määttä JA, Tvorogov D, Paatero I, Savisalo M, Silvennoinen O, Yarden Y, Elenius K.Differential nuclear localization and kinase activity of alternative ErbB4 intracellular domains.Oncogene. 2007 Oct 18;26(48):6905-14.