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ZFIN ID:
ZDB-PERS-150417-1
Jing, Chang-Bin
Email:
Chang-Bin_Jing@DFCI.HARVARD.EDU
URL:
Affiliation:
A. Thomas Look Lab
Address:
Department of Pediatric Oncology Dana-Farber Cancer Institute Harvard Medical School Mayer Building 630 450 Brookline Ave Boston, MA 02215 USA
Country:
United States
Phone:
Fax:
ORCID ID:
BIOGRAPHY AND RESEARCH INTERESTS
PUBLICATIONS
Jing, C.B., Prutsch, N., He, S., Zimmerman, M.W., Landesman, Y., Look, A.T. (2023) Synthetic lethal targeting of TET2-mutant haematopoietic stem and progenitor cells by XPO1 inhibitors. British journal of haematology. 201(3):489-501
Neelamraju, Y., Gjini, E., Chhangawala, S., Fan, H., He, S., Jing, C.B., Nguyen, A.T., Prajapati, S., Sheridan, C., Houvras, Y., Melnick, A., Look, A.T., Garrett-Bakelman, F.E. (2023) Depletion of
tet2
results in age-dependent changes in DNA methylation and gene expression in a zebrafish model of myelodysplastic syndrome. Frontiers in hematology. 2:
He, S., Zimmerman, M.W., Layden, H.M., Berezovskaya, A., Etchin, J., Martel, M.W., Thurston, G., Jing, C.B., van Rooijen, E., Kaufman, C.K., Rodig, S.J., Zon, L.I., Patton, E.E., Mansour, M.R., Look, A.T. (2021) Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss. Oncogene. 40(38):5718-5729
Jing, C.B., Fu, C., Prutsch, N., Wang, M., He, S., Look, A.T. (2020) Synthetic lethal targeting of TET2-mutant hematopoietic stem and progenitor cells (HSPCs) with TOP1-targeted drugs and PARP1 inhibitors. Leukemia. 34(11):2992-3006
Gjini, E., Jing, C.B., Nguyen, A.T., Reyon, D., Gans, E., Kesarsing, M., Peterson, J., Pozdnyakova, O., Rodig, S.J., Mansour, M.R., Joung, K., Look, A.T. (2019) Disruption of
asxl1
results in myeloproliferative neoplasms in zebrafish. Disease models & mechanisms. 12(5):
He, S., Jing, C.B., Look, A.T. (2017) Zebrafish models of leukemia. Methods in cell biology. 138:563-592
Jia, X.E., Ma, K., Xu, T., Gao, L., Wu, S., Fu, C., Zhang, W., Wang, Z., Liu, K., Dong, M., Jing, C., Ren, C., Dong, Z., Chen, Y., Jin, Y., Huang, Q., Chang, X., Deng, M., Li, L., Luo, L., Zhu, J., Dang, Y., Chang, H.C., Zon, L.I., Zhou, Y., Chen, S., Pan, W. (2015) Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell Research. 25(8):946-62
Gao, L., Li, D., Ma, K., Zhang, W., Xu, T., Fu, C., Jing, C., Jia, X., Wu, S., Sun, X., Dong, M., Deng, M., Chen, Y., Zhu, W., Peng, J., Wan, F., Zhou, Y., Zon, L.I., Pan, W. (2015) TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis. PLoS Genetics. 11:e1005346
Wang, S., Yin, J., Chen, D., Nie, F., Song, X., Fei, C., Miao, H., Jing, C., Ma, W., Wang, L., Xie, S., Li, C., Zeng, R., Pan, W., Hao, X., and Li, L. (2013) Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction. Nature Chemical Biology. 9(9):579-85
NON-ZEBRAFISH PUBLICATIONS
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