ZFIN ID: ZDB-PERS-140616-1
Don, Emily
Email: emily.don@mq.edu.au
URL: http://www.mq.edu.au/about/about-the-university/faculties-and-departments/faculty-of-medicine-and-health-sciences/staff-profiles/angela-laird
Affiliation: Laird Lab
Address: Faculty of Medicine & Health Sciences Level 1, 75 Talavera Road Macquarie University, NSW 2109
Country: Australia
Phone:
Fax:
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Cheng, F., De Luca, A., Hogan, A.L., Rayner, S.L., Davidson, J.M., Watchon, M., Stevens, C.H., Muñoz, S.S., Ooi, L., Yerbury, J.J., Don, E.K., Fifita, J.A., Villalva, M.D., Suddull, H., Chapman, T.R., Hedl, T.J., Walker, A.K., Yang, S., Morsch, M., Shi, B., Blair, I.P., Laird, A.S., Chung, R.S., Lee, A. (2021) Unbiased Label-Free Quantitative Proteomics of Cells Expressing Amyotrophic Lateral Sclerosis (ALS) Mutations in CCNF Reveals Activation of the Apoptosis Pathway: A Workflow to Screen Pathogenic Gene Mutations. Frontiers in molecular neuroscience. 14:627740
Don, E.K., Maschirow, A., Radford, R.A.W., Scherer, N.M., Vidal-Itriago, A., Hogan, A., Maurel, C., Formella, I., Stoddart, J.J., Hall, T.E., Lee, A., Shi, B., Cole, N.J., Laird, A.S., Badrock, A.P., Chung, R.S., Morsch, M. (2021) In vivo Validation of Bimolecular Fluorescence Complementation (BiFC) to Investigate Aggregate Formation in Amyotrophic Lateral Sclerosis (ALS). Molecular neurobiology. 58(5):2061-2074
Parakh, S., Shadfar, S., Perri, E.R., Ragagnin, A.M.G., Piattoni, C.V., Fogolín, M.B., Yuan, K.C., Shahheydari, H., Don, E.K., Thomas, C.J., Hong, Y., Comini, M.A., Laird, A.S., Spencer, D.M., Atkin, J.D. (2020) The Redox Activity of Protein Disulfide Isomerase Inhibits ALS Phenotypes in Cellular and Zebrafish Models. iScience. 23:101097
Pavez, M., Thompson, A.C., Arnott, H.J., Mitchell, C.B., D'Atri, I., Don, E.K., Chilton, J.K., Scott, E.K., Lin, J.Y., Young, K.M., Gasperini, R.J., Foa, L. (2019) STIM1 is required for remodelling of the endoplasmic reticulum and microtubule cytoskeleton in steering growth cones. The Journal of neuroscience : the official journal of the Society for Neuroscience. 39(26):5095-5114
Kumar, S.S., Tandberg, J.I., Penesyan, A., Elbourne, L.D.H., Suarez-Bosche, N., Don, E., Skadberg, E., Fenaroli, F., Cole, N., Winther-Larsen, H.C., Paulsen, I.T. (2018) Dual Transcriptomics of Host-Pathogen Interaction of Cystic Fibrosis Isolate Pseudomonas aeruginosa PASS1 With Zebrafish. Frontiers in cellular and infection microbiology. 8:406
Hogan, A.L., Don, E.K., Rayner, S.L., Lee, A., Laird, A.S., Watchon, M., Winnick, C., Tarr, I.S., Morsch, M., Fifita, J.A., Gwee, S.S.L., Formella, I., Hortle, E., Yuan, K.C., Molloy, M.P., Williams, K.L., Nicholson, G.A., Chung, R.S., Blair, I.P., Cole, N.J. (2018) Expression of ALS/FTD-linked mutant CCNF in zebrafish leads to increased cell death in the spinal cord and an aberrant motor phenotype. Human molecular genetics. 28(4):698
Robinson, K.J., Yuan, K.C., Don, E.K., Hogan, A.L., Winnick, C.G., Tym, M.C., Lucas, C.W., Shahheydari, H., Watchon, M., Blair, I.P., Atkin, J.D., Nicholson, G.A., Cole, N.J., Laird, A.S. (2018) Motor Neuron Abnormalities Correlate with Impaired Movement in Zebrafish that Express Mutant Superoxide Dismutase 1. Zebrafish. 16(1):8-14
Acosta, J.R., Watchon, M., Yuan, K.C., Fifita, J., Svahn, A.J., Don, E.K., Blair, I.P., Nicholson, G.A., Cole, N.J., Goldsbury, C., Laird, A.S. (2018) Neuronal cell culture from transgenic zebrafish models of neurodegenerative disease. Biology Open. 7(10):
Formella, I., Svahn, A.J., Radford, R.A.W., Don, E.K., Cole, N.J., Hogan, A., Lee, A., Chung, R.S., Morsch, M. (2018) Real-time visualization of oxidative stress-mediated neurodegeneration of individual spinal motor neurons in vivo. Redox Biology. 19:226-234
Svahn, A.J., Don, E.K., Badrock, A.P., Cole, N.J., Graeber, M.B., Yerbury, J.J., Chung, R., Morsch, M. (2018) Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons. Acta Neuropathologica. 136(3):445-459
Gwee, S.S.L., Radford, R.A.W., Chow, S., Syal, M.D., Morsch, M., Formella, I., Lee, A., Don, E.K., Badrock, A.P., Cole, N.J., West, A.K., Cheung, S.N.S., Chung, R.S. (2018) Aurora kinase B regulates axonal outgrowth and regeneration in the spinal motor neurons of developing zebrafish. Cellular and molecular life sciences : CMLS. 75(23):4269-4285
Lee, A., Rayner, S.L., Gwee, S.S.L., De Luca, A., Shahheydari, H., Sundaramoorthy, V., Ragagnin, A., Morsch, M., Radford, R., Galper, J., Freckleton, S., Shi, B., Walker, A.K., Don, E.K., Cole, N.J., Yang, S., Williams, K.L., Yerbury, J.J., Blair, I.P., Atkin, J.D., Molloy, M.P., Chung, R.S. (2017) Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy.. Cellular and molecular life sciences : CMLS. 75(2):335-354
Hogan, A.L., Don, E.K., Rayner, S.L., Lee, A., Laird, A.S., Watchon, M., Winnick, C., Tarr, I.S., Morsch, M., Fifita, J.A., Gwee, S., Formella, I., Hortle, E., Yuan, K., Molloy, M.P., Williams, K.L., Nicholson, G.A., Chung, R.S., Blair, I.P., Cole, N.J. (2017) Expression of ALS/FTD-linked mutant CCNF in zebrafish leads to increased cell death in the spinal cord and an aberrant motor phenotype. Human molecular genetics. 26(14):2616-2626
Morsch, M., Radford, R.A., Don, E.K., Lee, A., Hortle, E., Cole, N.J., Chung, R.S. (2017) Triggering Cell Stress and Death Using Conventional UV Laser Confocal Microscopy. Journal of visualized experiments : JoVE. (120)
Don, E.K., Formella, I., Badrock, A.P., Hall, T.E., Morsch, M., Hortle, E., Hogan, A., Chow, S., Gwee, S.S., Stoddart, J.J., Nicholson, G., Chung, R., Cole, N.J. (2017) A Tol2 Gateway-Compatible Toolbox for the Study of the Nervous System and Neurodegenerative Disease. Zebrafish. 14(1):69-72
Don, E.K., de Jong-Curtain, T.A., Doggett, K., Hall, T.E., Heng, B., Badrock, A.P., Winnick, C., Nicholson, G.A., Guillemin, G.J., Currie, P.D., Hesselson, D., Heath, J.K., Cole, N.J. (2016) Genetic basis of hindlimb loss in a naturally occurring vertebrate model. Biology Open. 5(3):359-66
Morsch, M., Radford, R., Lee, A., Don, E.K., Badrock, A.P., Hall, T.E., Cole, N.J., Chung, R. (2015) In vivo characterization of microglial engulfment of dying neurons in the zebrafish spinal cord. Frontiers in Cellular Neuroscience. 9:321
Acosta, J.R., Goldsbury, C., Winnick, C., Badrock, A.P., Fraser, S.T., Laird, A.S., Hall, T.E., Don, E.K., Fifita, J.A., Blair, I.P., Nicholson, G.A., Cole, N.J. (2014) Mutant Human FUS Is Ubiquitously Mislocalized and Generates Persistent Stress Granules in Primary Cultured Transgenic Zebrafish Cells. PLoS One. 9(6):e90572
Veilleux, H.D., Van Herwerden, L., Cole, N.J., Don, E.K., De Santis, C., Dixson, D.L., Wenger, A.S., and Munday, P.L. (2013) Otx2 expression and implications for olfactory imprinting in the anemonefish, Amphiprion percula. Biology Open. 2(9):907-915
Don, E.K., Currie, P.D., Cole, N.J. (2013) The evolutionary history of the development of the pelvic fin/hindlimb. Journal of anatomy. 222:114-133
Cole, N.J., Hall, T.E., Don, E.K., Berger, S., Boisvert, C.A., Neyt, C., Ericsson, R., Joss, J., Gurevich, D.B., and Currie, P.D. (2011) Development and evolution of the muscles of the pelvic fin. PLoS Biology. 9(10):e1001168
Don, E.K., Hall, T.E., Currie, P.D., and Cole, N.J. (2011) Morphology of pelvic fin loss in a zebrafish strain (Danio rerio). Journal of morphology. 272(5):583-589

NON-ZEBRAFISH PUBLICATIONS
Veilleux HD, Herwerden LV, Cole NJ, Don EK, De Santis C, Dixson DL, Wenger AS, Munday PL (2013). Otx2 expression and implications for olfactory imprinting in the anemonefish, Amphiprion percula Biology Open (doi: 10.1242).