ZFIN ID: ZDB-PERS-140515-1
van der Vaart, Michiel
Email: m.van.der.vaart@biology.leidenuniv.nl
URL:
Affiliation: Traver Lab
and also: Meijer Lab
Spaink Lab
Address:
Country:
Phone: +1 858-822-4659
Fax:
ORCID ID: 0000-0003-0828-7088


BIOGRAPHY AND RESEARCH INTERESTS
2014-present: UCSD, Traver lab (Post doc)
2009-2013: University of Leiden, Meijer lab (PhD student)


PUBLICATIONS
Muñoz-Sánchez, S., van der Vaart, M., Meijer, A.H. (2020) Autophagy and Lc3-Associated Phagocytosis in Zebrafish Models of Bacterial Infections. Cells. 9(11):
Zhang, R., Varela, M., Forn-Cuní, G., Torraca, V., van der Vaart, M., Meijer, A.H. (2020) Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages. Cell Death & Disease. 11:277
Puyskens, A., Stinn, A., van der Vaart, M., Kreuchwig, A., Protze, J., Pei, G., Klemm, M., Guhlich-Bornhof, U., Hurwitz, R., Krishnamoorthy, G., Schaaf, M., Krause, G., Meijer, A.H., Kaufmann, S.H.E., Moura-Alves, P. (2019) Aryl Hydrocarbon Receptor Modulation by Tuberculosis Drugs Impairs Host Defense and Treatment Outcomes. Cell Host & Microbe. 27(2):238-248.e7
Zhang, R., Varela, M., Vallentgoed, W., Forn-Cuni, G., van der Vaart, M., Meijer, A.H. (2019) The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection. PLoS pathogens. 15:e1007329
Masud, S., Prajsnar, T.K., Torraca, V., Lamers, G.E.M., Benning, M., Van Der Vaart, M., Meijer, A.H. (2019) Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model. Autophagy. 15(5):796-812
Troll, J.V., Hamilton, M.K., Abel, M.L., Ganz, J., Bates, J.M., Stephens, W.Z., Melancon, E., van der Vaart, M., Meijer, A.H., Distel, M., Eisen, J.S., Guillemin, K. (2018) Microbiota promote secretory cell determination in the intestinal epithelium by modulating host Notch signaling. Development (Cambridge, England). 145(4)
van der Vaart, M., Svoboda, O., Weijts, B.G., Espín-Palazón, R., Sapp, V., Pietri, T., Bagnat, M., Muotri, A.R., Traver, D. (2017) Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation.. Disease models & mechanisms. 10(12):1439-1451
Mesureur, J., Feliciano, J.R., Wagner, N., Gomes, M.C., Zhang, L., Blanco-Gonzalez, M., van der Vaart, M., O'Callaghan, D., Meijer, A.H., Vergunst, A.C. (2017) Macrophages, but not neutrophils, are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation. PLoS pathogens. 13:e1006437
Marín-Juez, R., Rovira, M., Crespo, D., van der Vaart, M., Spaink, H.P., Planas, J.V. (2015) GLUT2-mediated glucose uptake and availability are required for embryonic brain development in zebrafish. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 35(1):74-85
Varela, M., Romero, A., Dios, S., van der Vaart, M., Figueras, A., Meijer, A.H., Novoa, B. (2014) Cellular Visualization of Macrophage Pyroptosis and Interleukin-1β Release in a Viral Hemorrhagic Infection in Zebrafish Larvae. Journal of virology. 88(20):12026-40
Fenaroli, F., Westmoreland, D., Benjaminsen, J., Kolstad, T., Skjeldal, F.M., Meijer, A., van der Vaart, M., Ulanova, L., Roos, N., Nyström, B., Hildahl, J., Griffiths, G. (2014) Nanoparticles as Drug Delivery System against Tuberculosis in Zebrafish Embryos: Direct Visualization and Treatment. ACS nano. 8(7):7014-26
Elks, P.M., van der Vaart, M., van Hensbergen, V., Schutz, E., Redd, M.J., Murayama, E., Spaink, H.P., Meijer, A.H. (2014) Mycobacteria Counteract a TLR-Mediated Nitrosative Defense Mechanism in a Zebrafish Infection Model. PLoS One. 9:e100928
van der Vaart, M., Korbee, C.J., Lamers, G.E., Tengeler, A.C., Hosseini, R., Haks, M.C., Ottenhoff, T.H., Spaink, H.P., Meijer, A.H. (2014) The DNA Damage-Regulated Autophagy Modulator DRAM1 Links Mycobacterial Recognition via TLR-MYD88 to Autophagic Defense. Cell Host & Microbe. 15(6):753-767
Meijer, A.H., van der Vaart, M. (2014) DRAM1 promotes the targeting of mycobacteria to selective autophagy. Autophagy. 10(12):2389-91
Meijer, A.H., van der Vaart, M., and Spaink, H.P. (2014) Real-time imaging and genetic dissection of host-microbe interactions in zebrafish. Cellular Microbiology. 16(1):39-49
van der Vaart, M., van Soest, J.J., Spaink, H.P., and Meijer, A.H. (2013) Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system. Disease models & mechanisms. 6(3):841-54
Elks, P.M., Brizee, S., van der Vaart, M., Walmsley, S.R., van Eeden, F.J., Renshaw, S.A., and Meijer, A.H. (2013) Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism. PLoS pathogens. 9(12):e1003789
van der Vaart, M., Spaink, H.P., and Meijer, A.H. (2012) Pathogen Recognition and Activation of the Innate Immune Response in Zebrafish. Advances in hematology. 2012:159807
Cui, C., Benard, E.L., Kanwal, Z., Stockhammer, O.W., van der Vaart, M., Zakrzewska, A., Spaink, H.P., and Meijer, A.H. (2011) Infectious disease modeling and innate immune function in zebrafish embryos. Methods in cell biology. 105:273-308
van der Vaart, M., and Schaaf, M.J. (2009) Naturally occurring C-terminal splice variants of nuclear receptors. Nuclear receptor signaling. 7:e007

NON-ZEBRAFISH PUBLICATIONS