ZFIN ID: ZDB-PERS-131009-8
Widrick, Jeffrey
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Affiliation: Kunkel Lab
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Country: United States
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BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Widrick, J.J., Lambert, M.R., Kunkel, L.M., Beggs, A.H. (2023) Optimizing assays of zebrafish larvae swimming performance for drug discovery. Expert opinion on drug discovery. 18(6):629-641
Rutkove, S.B., Callegari, S., Concepcion, H., Mourey, T., Widrick, J., Nagy, J.A., Nath, A.K. (2023) Electrical impedance myography detects age-related skeletal muscle atrophy in adult zebrafish. Scientific Reports. 13:71917191
Hightower, R.M., Reid, A.L., Gibbs, D.E., Wang, Y., Widrick, J.J., Kunkel, L.M., Kastenschmidt, J.M., Villalta, S.A., van Groen, T., Chang, H., Gornisiewicz, S., Landesman, Y., Tamir, S., Alexander, M.S. (2019) The SINE Compound KPT-350 Blocks Dystrophic Pathologies in DMD Zebrafish and Mice. Molecular therapy : the journal of the American Society of Gene Therapy. 28(1):189-201
Widrick, J.J., Kawahara, G., Alexander, M.S., Beggs, A.H., Kunkel, L.M. (2019) Discovery of Novel Therapeutics for Muscular Dystrophies using Zebrafish Phenotypic Screens. Journal of neuromuscular diseases. 6(3):271-287
Pakula, A., Lek, A., Widrick, J., Mitsuhashi, H., Bugda Gwilt, K.M., Gupta, V.M., Rahimov, F., Criscione, J., Zhang, Y., Gibbs, D., Murphy, Q., Manglik, A., Mead, L., Kunkel, L. (2018) Transgenic zebrafish model of DUX4 misexpression reveals a developmental role in FSHD pathogenesis. Human molecular genetics. 28(2):320-331
Serafini, P.R., Feyder, M.J., Hightower, R.M., Garcia-Perez, D., Vieira, N.M., Lek, A., Gibbs, D.E., Moukha-Chafiq, O., Augelli-Szafran, C.E., Kawahara, G., Widrick, J.J., Kunkel, L.M., Alexander, M.S. (2018) A limb-girdle muscular dystrophy 2I model of muscular dystrophy identifies corrective drug compounds for dystroglycanopathies. JCI insight. 3(18):
Widrick, J.J., Gibbs, D.E., Sanchez, B., Gupta, V.A., Pakula, A., Lawrence, C., Beggs, A.H., Kunkel, L.M. (2018) An open source microcontroller based flume for evaluating swimming performance of larval, juvenile, and adult zebrafish. PLoS One. 13:e0199712
Bennett, A.H., O'Donohue, M.F., Gundry, S.R., Chan, A.T., Widrick, J., Draper, I., Chakraborty, A., Zhou, Y., Zon, L.I., Gleizes, P.E., Beggs, A.H., Gupta, V.A. (2018) RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes. PLoS Genetics. 14:e1007226
Widrick, J.J., Alexander, M., Sanchez, B., Gibbs, D., Kawahara, G., Beggs, A., Kunkel, L. (2016) Muscle dysfunction in a zebrafish model of Duchenne muscular dystrophy. Physiological Genomics. 48(11):850-860
Kawahara, G., Gasperini, M.J., Myers, J.A., Widrick, J.J., Eran, A., Serafini, P.R., Alexander, M.S., Pletcher, M.T., Morris, C.A., and Kunkel, L.M. (2014) Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling. Human molecular genetics. 23(7):1869-78

NON-ZEBRAFISH PUBLICATIONS