ZFIN ID: ZDB-PERS-130212-3
Opitz, Robert
Email: r.opitz@excite.com
URL:
Affiliation: Costagliola Lab
Address:
Country: Belgium
Phone:
Fax:
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Barone, M., Müller, M., Chiha, S., Ren, J., Albat, D., Soicke, A., Dohmen, S., Klein, M., Bruns, J., van Dinther, M., Opitz, R., Lindemann, P., Beerbaum, M., Motzny, K., Roske, Y., Schmieder, P., Volkmer, R., Nazaré, M., Heinemann, U., Oschkinat, H., Ten Dijke, P., Schmalz, H.G., Kühne, R. (2020) Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 117(47):29684-29690
Giusti, N., Gillotay, P., Trubiroha, A., Opitz, R., Dumont, J.E., Costagliola, S., De Deken, X. (2019) Inhibition of the thyroid hormonogenic H2O2 production by Duox/DuoxA in zebrafish reveals VAS2870 as a new goitrogenic compound. Molecular and Cellular Endocrinology. 500:110635
Trubiroha, A., Gillotay, P., Giusti, N., Gacquer, D., Libert, F., Lefort, A., Haerlingen, B., De Deken, X., Opitz, R., Costagliola, S. (2018) A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function. Scientific Reports. 8:5647
Opitz, R., Hitz, M.P., Vandernoot, I., Trubiroha, A., Abu-Khudir, R., Samuels, M., Désilets, V., Costagliola, S., Andelfinger, G., Deladoëy, J. (2015) Functional Zebrafish Studies Based on Human Genotyping Point to Netrin-1 as a Link Between Aberrant Cardiovascular Development and Thyroid Dysgenesis. Endocrinology. 1(1):377-88
Opitz, R., Antonica, F., Costagliola, S. (2013) New Model Systems to Illuminate Thyroid Organogenesis. Part I: An Update on the Zebrafish Toolbox. European thyroid journal. 2:229-242
Opitz, R., Maquet, E., Zoenen, M., Dadhich, R., and Costagliola, S. (2011) TSH Receptor Function Is Required for Normal Thyroid Differentiation in Zebrafish. Molecular endocrinology (Baltimore, Md.). 25(9):1579-99

NON-ZEBRAFISH PUBLICATIONS