ZFIN ID: ZDB-PERS-050428-23
Löhr, Heiko
Email: loehrh@uni-koeln.de
URL:
Affiliation: Driever Lab
Address: Institute for Developmental Biology Cologne University Biocenter Zuelpicher Strasse 47b Cologne, D-50674 Germany
Country: Germany
Phone:
Fax:
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Reinoß, P., Ciglieri, E., Minére, M., Bremser, S., Klein, A., Löhr, H., Fuller, P.M., Büschges, A., Kloppenburg, P., Fenselau, H., Hammerschmidt, M. (2020) Hypothalamic Pomc Neurons Innervate the Spinal Cord and Modulate the Excitability of Premotor Circuits. Current biology : CB. 30(23):4579-4593.e7
Di Bella, D.J., Carcagno, A.L., Bartolomeu, M.L., Pardi, M.B., Löhr, H., Siegel, N., Hammerschmidt, M., Marín-Burgin, A., Lanuza, G.M. (2019) Ascl1 Balances Neuronal versus Ependymal Fate in the Spinal Cord Central Canal. Cell Reports. 28:2264-2274.e3
Löhr, H., Hess, S., Pereira, M.M.A., Reinoß, P., Leibold, S., Schenkel, C., Wunderlich, C.M., Kloppenburg, P., Brüning, J.C., Hammerschmidt, M. (2018) Diet-Induced Growth Is Regulated via Acquired Leptin Resistance and Engages a Pomc-Somatostatin-Growth Hormone Circuit. Cell Reports. 23:1728-1741
Pogoda, H.M., Riedl-Quinkertz, I., Löhr, H., Waxman, J.S., Dale, R.M., Topczewski, J., Schulte-Merker, S., Hammerschmidt, M. (2018) Direct activation of chordoblasts by retinoic acid is required for segmented centra mineralization during zebrafish spine development. Development (Cambridge, England). 145(9)
Mendoza-Ferreira, N., Coutelier, M., Janzen, E., Hosseinibarkooie, S., Löhr, H., Schneider, S., Milbradt, J., Karakaya, M., Riessland, M., Pichlo, C., Torres-Benito, L., Singleton, A., Zuchner, S., Brice, A., Durr, A., Hammerschmidt, M., Stevanin, G., Wirth, B. (2018) Biallelic CHP1 mutation causes human autosomal recessive ataxia by impairing NHE1 function. Neurology. Genetics. 4:e209
Riessland, M., Kaczmarek, A., Schneider, S., Swoboda, K.J., Löhr, H., Bradler, C., Grysko, V., Dimitriadi, M., Hosseinibarkooie, S., Torres-Benito, L., Peters, M., Upadhyay, A., Biglari, N., Kröber, S., Hölker, I., Garbes, L., Gilissen, C., Hoischen, A., Nürnberg, G., Nürnberg, P., Walter, M., Rigo, F., Bennett, C.F., Kye, M.J., Hart, A.C., Hammerschmidt, M., Kloppenburg, P., Wirth, B. (2017) Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis. American journal of human genetics. 100(2):297-315
Martinez, A.F., Abe, Y., Hong, S., Molyneux, K., Yarnell, D., Löhr, H., Driever, W., Acosta, M.T., Arcos-Burgos, M., Muenke, M. (2016) An Ultraconserved Brain-Specific Enhancer Within ADGRL3 (LPHN3) Underpins Attention-Deficit/Hyperactivity Disorder Susceptibility. Biological psychiatry. 80(12):943-954
Koch, P., Löhr, H.B., Driever, W. (2014) A Mutation in cnot8, Component of the Ccr4-Not Complex Regulating Transcript Stability, Affects Expression Levels of Developmental Regulators and Reveals a Role of Fgf3 in Development of Caudal Hypothalamic Dopaminergic Neurons. PLoS One. 9:e113829
Liu, F., Pogoda, H.M., Pearson, C.A., Ohyama, K., Löhr, H., Hammerschmidt, M., and Placzek, M. (2013) Direct and indirect roles of Fgf3 and Fgf10 in innervation and vascularisation of the vertebrate hypothalamic neurohypophysis. Development (Cambridge, England). 140(5):1111-1122
Schweitzer, J., Löhr, H., Bonkowsky, J.L., Hübscher, K., and Driever, W. (2013) Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. Development (Cambridge, England). 140(1):93-106
Schweitzer, J., Löhr, H., Filippi, A., and Driever, W. (2012) Dopaminergic and noradrenergic circuit development in zebrafish. Developmental Neurobiology. 72(3):256-268
Löhr, H., and Hammerschmidt, M. (2011) Zebrafish in endocrine systems: recent advances and implications for human disease. Annual review of physiology. 73:183-211
Löhr, H., Ryu, S., and Driever, W. (2009) Zebrafish diencephalic A11-related dopaminergic neurons share a conserved transcriptional network with neuroendocrine cell lineages. Development (Cambridge, England). 136(6):1007-1017
Löhr, H.B. (2009) A genetic screen for mutations affecting development of catecholaminergic systems in zebrafish reveals a novel role for the transcription factors Arnt2 and Sim1. Ph.D. Thesis. :199p

NON-ZEBRAFISH PUBLICATIONS