ZFIN Lab: Rodriguez Lab

ZFIN ID: ZDB-LAB-990729-25

Rodriguez Lab

PI/Director:	Rodriguez, Raquel E.
Contact Person:	Rodriguez, Raquel E.
URL:
Address:	Department of Biochemistry and Molecular Biology Institute of Neuroscience Faculty of Medicine University of Salamanca Salamanca, 37007 Spain including Canary Islands, Ceuta and Melilla
Country:	Spain
Phone:	34-923-294626
Fax:	34-923-294750
Line Designation:	None assigned

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Herrero, Javier Post-Doc	Rodriguez-Martin, Ivan Post-Doc	Macho, Fatima Graduate Student
Marrón, Ezequiel Graduate Student

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Calderon-Garcia, A.A., Perez-Fernandez, M., Curto-Aguilera, D., Rodriguez-Martin, I., Sánchez-Barba, M., Gonzalez-Nunez, V. (2022) Exposure to Morphine and Cocaine Modify the Transcriptomic Landscape in Zebrafish Embryos. Neuroscience. 507:14-27

Garcia-Concejo, A., Jimenez-Gonzalez, A., Rodriguez, R.E. (2018) Opioid and Notch signaling pathways are reciprocally regulated through miR- 29a and miR-212 expression. Biochimica et biophysica acta. General subjects. 1862:2605-2612

Jimenez-Gonzalez, A., García-Concejo, A., León-Lobera, F., Rodriguez, R.E. (2017) Morphine delays neural stem cells differentiation by facilitating Nestin overexpression. Biochimica et biophysica acta. 1862(3):474-484

Jimenez-Gonzalez, A., García-Concejo, A., López-Benito, S., Gonzalez-Nunez, V., Arévalo, J.C., Rodriguez, R.E. (2016) Role of morphine, miR-212/132 and mu opioid receptor in the regulation of bdnf in zebrafish embryos. Biochimica et biophysica acta. General subjects. 1860(6):1308-16

Pignatelli, M., Vilella, A.J., Muffato, M., Gordon, L., White, S., Flicek, P., Herrero, J. (2016) ncRNA orthologies in the vertebrate lineage. Database : the journal of biological databases and curation. 2016

Howe, K., Clark, M.D., Torroja, C.F., Torrance, J., Berthelot, C., Muffato, M., Collins, J.E., Humphray, S., McLaren, K., Matthews, L., McLaren, S., Sealy, I., Caccamo, M., Churcher, C., Scott, C., Barrett, J.C., Koch, R., Rauch, G.J., White, S., Chow, W., Kilian, B., Quintais, L.T., Guerra-Assunção, J.A., Zhou, Y., Gu, Y., Yen, J., Vogel, J.H., Eyre, T., Redmond, S., Banerjee, R., Chi, J., Fu, B., Langley, E., Maguire, S.F., Laird, G.K., Lloyd, D., Kenyon, E., Donaldson, S., Sehra, H., Almeida-King, J., Loveland, J., Trevanion, S., Jones, M., Quail, M., Willey, D., Hunt, A., Burton, J., Sims, S., McLay, K., Plumb, B., Davis, J., Clee, C., Oliver, K., Clark, R., Riddle, C., Eliott, D., Threadgold, G., Harden, G., Ware, D., Mortimer, B., Kerry, G., Heath, P., Phillimore, B., Tracey, A., Corby, N., Dunn, M., Johnson, C., Wood, J., Clark, S., Pelan, S., Griffiths, G., Smith, M., Glithero, R., Howden, P., Barker, N., Stevens, C., Harley, J., Holt, K., Panagiotidis, G., Lovell, J., Beasley, H., Henderson, C., Gordon, D., Auger, K., Wright, D., Collins, J., Raisen, C., Dyer, L., Leung, K., Robertson, L., Ambridge, K., Leongamornlert, D., McGuire, S., Gilderthorp, R., Griffiths, C., Manthravadi, D., Nichol, S., Barker, G., Whitehead, S., Kay, M., Brown, J., Murnane, C., Gray, E., Humphries, M., Sycamore, N., Barker, D., Saunders, D., Wallis, J., Babbage, A., Hammond, S., Mashreghi-Mohammadi, M., Barr, L., Martin, S., Wray, P., Ellington, A., Matthews, N., Ellwood, M., Woodmansey, R., Clark, G., Cooper, J., Tromans, A., Grafham, D., Skuce, C., Pandian, R., Andrews, R., Harrison, E., Kimberley, A., Garnett, J., Fosker, N., Hall, R., Garner, P., Kelly, D., Bird, C., Palmer, S., Gehring, I., Berger, A., Dooley, C.M., Ersan-Ürün, Z., Eser, C., Geiger, H., Geisler, M., Karotki, L., Kirn, A., Konantz, J., Konantz, M., Oberländer, M., Rudolph-Geiger, S., Teucke, M., Osoegawa, K., Zhu, B., Rapp, A., Widaa, S., Langford, C., Yang, F., Carter, N.P., Harrow, J., Ning, Z., Herrero, J., Searle, S.M., Enright, A., Geisler, R., Plasterk, R.H., Lee, C., Westerfield, M., de Jong, P.J., Zon, L.I., Postlethwait, J.H., Nüsslein-Volhard, C., Hubbard, T.J., Crollius, H.R., Rogers, J., and Stemple, D.L. (2013) The zebrafish reference genome sequence and its relationship to the human genome. Nature. 496:498-503

López-Bellido, R., Barreto-Valer, K., and Rodriguez, R.E. (2013) Expression of tachykinin receptors in zebrafish: influence of cocaine and opioid receptors. Journal of molecular endocrinology. 50(2):115-129

Flicek, P., Ahmed, I., Amode, M.R., Barrell, D., Beal, K., Brent, S., Carvalho-Silva, D., Clapham, P., Coates, G., Fairley, S., Fitzgerald, S., Gil, L., García-Girón, C., Gordon, L., Hourlier, T., Hunt, S., Juettemann, T., Kähäri, A.K., Keenan, S., Komorowska, M., Kulesha, E., Longden, I., Maurel, T., McLaren, W.M., Muffato, M., Nag, R., Overduin, B., Pignatelli, M., Pritchard, B., Pritchard, E., Riat, H.S., Ritchie, G.R., Ruffier, M., Schuster, M., Sheppard, D., Sobral, D., Taylor, K., Thormann, A., Trevanion, S., White, S., Wilder, S.P., Aken, B.L., Birney, E., Cunningham, F., Dunham, I., Harrow, J., Herrero, J., Hubbard, T.J., Johnson, N., Kinsella, R., Parker, A., Spudich, G., Yates, A., Zadissa, A., and Searle, S.M. (2013) Ensembl 2013. Nucleic acids research. 41(D1):D48-55

Sanchez-Simon, F.M., Ledo, A.S., Arevalo, R.A., and Rodriguez, R.E. (2012) New insights into opioid regulatory pathways: influence of opioids on Wnt1 expression in zebrafish embryos. Neuroscience. 200:237-47

Rivas-Boyero, A.A., Herrero-Turrion, M.J., Gonzalez-Nunez, V., Sanchez-Simon, F.M., Barreto-Valer, K., and Rodriguez, R.E. (2011) Pharmacological characterization of a nociceptin receptor from zebrafish (Danio rerio). Journal of molecular endocrinology. 46(2):111-123

Flicek, P., Amode, M.R., Barrell, D., Beal, K., Brent, S., Chen, Y., Clapham, P., Coates, G., Fairley, S., Fitzgerald, S., Gordon, L., Hendrix, M., Hourlier, T., Johnson, N., Kahari, A., Keefe, D., Keenan, S., Kinsella, R., Kokocinski, F., Kulesha, E., Larsson, P., Longden, I., McLaren, W., Overduin, B., Pritchard, B., Riat, H.S., Rios, D., Ritchie, G.R., Ruffier, M., Schuster, M., Sobral, D., Spudich, G., Tang, Y.A., Trevanion, S., Vandrovcova, J., Vilella, A.J., White, S., Wilder, S.P., Zadissa, A., Zamora, J., Aken, B.L., Birney, E., Cunningham, F., Dunham, I., Durbin, R., Fernandez-Suarez, X.M., Herrero, J., Hubbard, T.J., Parker, A., Proctor, G., Vogel, J., and Searle, S.M. (2011) Ensembl 2011. Nucleic acids research. 39(suppl 1):D800-D806

Sanchez-Simon, F.M., Zhang, X.X., Loh, H.H., Law, P.Y., and Rodriguez, R.E. (2010) Morphine regulates dopaminergic neuron differentiation via miR-133b. Molecular pharmacology. 78(5):935-942

Sanchez-Simon, F.M., Arenzana, F.J., and Rodriguez, R.E. (2010) In vivo effects of morphine on neuronal fate and opioid receptor expression in zebrafish embryos. The European journal of neuroscience. 32(4):550-559

Macho Sanchez-Simon, F., and Rodriguez, R.E. (2009) Expression of the nociceptin receptor during zebrafish development: influence of morphine and nociceptin. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 27(4):315-320

Macho Sanchez-Simon, F., and Rodriguez, R.E. (2008) Developmental expression and distribution of opioid receptors in zebrafish. Neuroscience. 151(1):129-137

Rodriguez-Martin, I., Herrero-Turrion, M.J., Marron Fdez de Velasco, E., Gonzalez-Sarmiento, R., and Rodriguez, R.E. (2007) Characterization of two duplicate zebrafish Cb2-like cannabinoid receptors. Gene. 389(1):36-44

Rodriguez-Martin, I., de Velasco, E.M., and Rodriguez, R.E. (2007) Characterization of cannabinoid-binding sites in zebrafish brain. Neuroscience letters. 413(3):249-254

Pinal-Seoane, N., Martin, I.R., Gonzalez-Nunez, V., de Velasco, E.M., Alvarez, F.A., Sarmiento, R.G., and Rodriguez, R.E. (2006) Characterization of a new duplicate {delta}-opioid receptor from zebrafish. Journal of molecular endocrinology. 37(3):391-403

Alvarez, F.A., Rodriguez-Martin, I., Gonzalez-Nuñez, V., de Velasco, E.M., Gonzalez Sarmiento, R., and Rodriguez, R.E. (2006) New kappa opioid receptor from zebrafish Danio rerio. Neuroscience letters. 405(1-2):94-99

Gonzalez-Nuñez, V., Barrallo, A., Traynor, J.R., and Rodriguez, R.E. (2006) Characterization of Opioid-Binding Sites in Zebrafish Brain. The Journal of pharmacology and experimental therapeutics. 316(2):900-904

Gonzalez-Nuñez, V., Arsequell, G., Szemenyei, E., Toth, G., Valencia, G., and Rodriguez, R.E. (2005) Binding profile of the endogenous novel heptapeptide met-enkephalin-gly-tyr in zebrafish and rat brain. The Journal of pharmacology and experimental therapeutics. 314(2):862-867

Gonzalez-Nuñez, V., Gonzalez-Sarmiento, R., and Rodriguez, R.E. (2003) Identification of two proopiomelanocortin genes in zebrafish (Danio rerio). Brain research. Molecular brain research. 120(1):1-8

Gonzalez-Nuñez, V., Gonzalez-Sarmiento, R., and Rodriguez, R.E. (2003) Cloning and characterization of a full-length pronociceptin in zebrafish: evidence of the existence of two different nociceptin sequences in the same precursor. BBA Gene Structure and Expression. 1629(1-3):114-118

González Nuñez, V., González Sarmiento, R., and Rodriguez, R.E. (2003) Characterization of zebrafish proenkephalin reveals novel opioid sequences. Mol. Brain Res.. 114(1):31-39

Barrallo, A., González Sarmiento, R., Alvar, F., and Rodriguez, R.E. (2000) ZFOR2, a new opioid receptor-like gene from the teleost zebrafish (Danio rerio). Brain research. Molecular brain research. 84(1-2):1-6

Rodriguez, R.E., Barrallo, A., Garcia Malvar, F., McFadyen, I.J., González Sarmiento, R., and Traynor, J.R. (2000) Characterization of ZFOR1, a putative delta-opioid receptor from the teleost zebrafish (Danio rerio). Neuroscience letters. 288(3):207-210

Porteros, A., García Isidoro, M., Barrallo, A., González Sarmiento, R., and Rodriguez, R.E. (1999) Expression of ZFOR1, a delta-opioid receptor, in the central nervous system of the zebrafish (Danio rerio). The Journal of comparative neurology. 412(3):429-438

Barrallo, A., González Sarmiento, R., García Isidoro, M., Cidad, P., Porteros, A., Rodriguez, R.E. (1999) Differential brain expression of a new ß-actin gene from zebrafish (Danio rerio). The European journal of neuroscience. 11:369-372

Barrallo, A., González Sarmiento, R., Porteros, A., García Isidoro, M., and Rodriguez, R.E. (1998) Cloning, molecular characterization, and distribution of a gene homologous to delta opioid receptor from zebrafish (Danio rerio). Biochemical and Biophysical Research Communications. 245:544-548