ZFIN ID: ZDB-LAB-970418-21
Différenciation Cellulaire et Croissance
PI/Director:
Co-PI / Senior
Researcher:
Bonnieu, Anne
Chatonnet, Arnaud
Contact Person: Chatonnet, Arnaud
Email: chatonne@ensam.inra.fr
URL: http://compact.jouy.inra.fr:8888/compact/consulter98/external/unites/ecrans/866
Address: Departement de Physiologie Animale Institut National de la Recherche Agronomique 2, Place Pierre Viala Cedex 1 Montpellier, 34060 France
Country: France
Phone: 33-4-99-61-28-14
Fax: 33-4-67-54-56-94
Line Designation: None assigned


GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available


STATEMENT OF RESEARCH INTERESTS
The main focus of the lab is identifying gene networks involved in the control of early steps of muscle differentiation. We are in particular interested in the regulation of myogenesis by retinoic acid.

To do so, we use candidate genes, transcriptome and promoter analysis approaches.

We are also investigating the role of acetylcholinesterase and related enzymes during development.


LAB MEMBERS


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Chatonnet, A., Lenfant, N., Marchot, P., Selkirk, M.E. (2017) Natural genomic amplification of cholinesterase genes in animals. Journal of neurochemistry. 142 Suppl 2:73-81
Kitzmann, M., Bonnieu, A., Duret, C., Vernus, B., Barro, M., Laoudj-Chenivesse, D., Verdi, J.M., and Carnac, G. (2006) Inhibition of Notch signaling induces myotube hypertrophy by recruiting a subpopulation of reserve cells. Journal of Cellular Physiology. 208(3):538-548
Hamade, A., Deries, M., Begemann, G., Bally-Cuif, L., Genet, C., Sabatier, F., Bonnieu, A., and Cousin, X. (2006) Retinoic acid activates myogenesis in vivo through Fgf8 signalling. Developmental Biology. 289(1):127-140
Behra, M., Cousin, X., Bertrand, C., Vonesch, J.L., Biellmann, D., Chatonnet, A., and Strähle, U. (2002) Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo. Nature Neuroscience. 5(2):111-118
Bertrand, C., Chatonnet, A., Takke, C., Yan, Y.-L., Postlethwait, J., Toutant, J.P., and Cousin, X. (2001) Zebrafish Acetylcholinesterase Is Encoded by a Single Gene Localized on Linkage Group 7: Gene structure and polymorphism; molecular forms and expression pattern during development. The Journal of biological chemistry. 276(1):464-474
Cousin, X., Hotelier, T., Giles, K., Lievin, P., Toutant, J.P., and Chatonnet, A. (1997) The alpha/beta fold family of proteins database and the cholinesterase gene server ESTHER. Nucleic acids research. 25:143-146