ZFIN Lab: Molecular Genetics Laboratory

ZFIN ID: ZDB-LAB-231018-1

ZFIN ID: ZDB-LAB-231018-1

Molecular Genetics Laboratory

PI/Director:	Lee, Yoonsung
Contact Person:	Lee, Yoonsung
Email:	ylee3699@khu.ac.kr
URL:	https://khuttrcenter.wordpress.com/home/mgl/
Address:	892, Dongnam-ro, Gangdong-gu, Seoul, Republic of Korea, 05278
Country:	South Korea
Phone:	+82-2-440-6290
Fax:	+82-2-440-8109
Line Designation:	kh

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show first 50 of 67 genomic features

STATEMENT OF RESEARCH INTERESTS

Using the zebrafish model system, our group aims to understand biological phenomena and pathological mechanisms related to hematopoiesis and DNA repair processes in vivo.

LAB MEMBERS

Ji, Sang-gu Graduate Student	Nam, Uijeong Graduate Student	Ye, Qianying Graduate Student
Yun, Sojin Graduate Student	Lee, Nahyun Technical Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Lee, S., Ye, Q., Yang, H., Lee, S., Kim, Y., Lee, N., Gonzalez-Cox, D., Yi, D.K., Kim, S.Y., Choi, S., Choi, T., Kim, M.S., Hong, S.S., Choi, C.W., Lee, Y., Park, Y.H. (2024) Aiouea padiformis extract exhibits anti-inflammatory effects by inhibiting the ATPase activity of NLRP3. Scientific Reports. 14:52375237

Lee, S., Yun, S., Yang, H., Lee, N., Kim, Y., Lee, S., Zamora, N.A., Montero, S.S., Yi, D.K., Kim, S.Y., Choi, S., Choi, T., Kim, M.S., Lee, Y., Park, Y.H. (2024) Guarea microcarpa C. DC. extract inhibits NLRP3 inflammasome by suppressing its ATPase activity. Journal of ethnopharmacology. 323:117711

Shin, U., Nakhro, K., Oh, C.K., Carrington, B., Song, H., Varshney, G.K., Kim, Y., Song, H., Jeon, S., Robbins, G., Kim, S., Yoon, S., Choi, Y.J., Kim, Y.J., Burgess, S., Kang, S., Sood, R., Lee, Y., Myung, K. (2021) Large-scale generation and phenotypic characterization of zebrafish CRISPR mutants of DNA repair genes. DNA repair. 107:103173

Han, S.H., Kim, S.H., Kim, H.J., Lee, Y., Choi, S.Y., Park, G., Kim, D.H., Lee, A., Kim, J., Choi, J.M., Kim, Y., Myung, K., Kim, H., Kim, D.W. (2017) Cobll1 is linked to drug resistance and blastic transformation in chronic myeloid leukemia. Leukemia. 31(7):1532-1539

Lee, Y., Manegold, J.E., Kim, A.D., Pouget, C., Stachura, D.L., Clements, W.K., Traver, D. (2014) FGF signalling specifies haematopoietic stem cells through its regulation of somitic Notch signalling. Nature communications. 5:5583

Pouget, C., Peterkin, T., Simões, F.C., Lee, Y., Traver, D., Patient, R. (2014) FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway. Nature communications. 5:5588

Shin, D., Lee, Y., Poss, K.D., and Stainier, D.Y. (2011) Restriction of hepatic competence by Fgf signaling. Development (Cambridge, England). 138(7):1339-1348

Lee, Y., Nachtrab, G., Klinsawat, P.W., Hami, D., and Poss, K.D. (2010) Ras controls melanocyte expansion during zebrafish fin stripe regeneration. Disease models & mechanisms. 3(7-8):496-503

Gonzalez-Quevedo, R., Lee, Y., Poss, K.D., and Wilkinson, D.G. (2010) Neuronal Regulation of the Spatial Patterning of Neurogenesis. Developmental Cell. 18(1):136-147

Lee, Y., Hami, D., De Val, S., Kagermeier-Schenk, B., Wills, A.A., Black, B.L., Weidinger, G., and Poss, K.D. (2009) Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins. Developmental Biology. 331(2):270-280

Lee, Y. (2009) Regulation of Progenitor Cell Proliferation During Zebrafish Fin Regeneration. Thesis.

Marques, S.R., Lee, Y., Poss, K.D., and Yelon, D. (2008) Reiterative roles for FGF signaling in the establishment of size and proportion of the zebrafish heart. Developmental Biology. 321(2):397-406

Lee, Y., Grill, S., Sanchez, A., Murphy-Ryan, M., Poss, K.D. (2005) Fgf signaling instructs position-dependent growth rate during zebrafish fin regeneration. Development (Cambridge, England). 132(23):5173-5183