ZFIN Lab: Kaslin Lab

ZFIN ID: ZDB-LAB-220328-1

Kaslin Lab

PI/Director:	Kaslin, Jan
Contact Person:	Kaslin, Jan
Email:	Jan.Kaslin@monash.edu
URL:	http://www.armi.org.au/
Address:	Associate Professor, Jan Kaslin, PhD, Group Leader Australian Regenerative Medicine Institute, 15 Innovation Walk, Level 1, Building 75, Monash University Clayton Campus, Clayton, Victoria 3800, Australia
Country:	Australia
Phone:	+61 3 9902 9613
Fax:	+61 3 9902 9729
Line Designation:	mnu

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 1 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Henry, J., Bai, Y., Kreuder, F., Saaristo, M., Kaslin, J., Wlodkowic, D. (2022) A miniaturized electrothermal array for rapid analysis of temperature preference behaviors in ecology and ecotoxicology. Environmental pollution (Barking, Essex : 1987). 314:120202

Lever, J., Kreuder, F., Henry, J., Hung, A., Allard, P.M., Brkljača, R., Rix, C., Taki, A.C., Gasser, R.B., Kaslin, J., Wlodkowic, D., Wolfender, J.L., Urban, S. (2022) Targeted Isolation of Antibiotic Brominated Alkaloids from the Marine Sponge Pseudoceratina durissima Using Virtual Screening and Molecular Networking. Marine drugs. 20(9)

Henry, J., Bai, Y., Kreuder, F., Saaristo, M., Kaslin, J., Wlodkowic, D. (2022) Sensory-Motor Perturbations in Larval Zebrafish (Danio rerio) Induced by Exposure to Low Levels of Neuroactive Micropollutants during Development. International Journal of Molecular Sciences. 23(16)

Henry, J., Bai, Y., Kreuder, F., Mawdsley, D., Kaslin, J., Wlodkowic, D. (2022) Accelerating Chemobehavioral Phenotypic Screening in Neurotoxicology Using a Living Embryo Array System. Zebrafish. 19(1):32-35

Kurolap, A., Kreuder, F., Gonzaga-Jauregui, C., Duvdevani, M.P., Harel, T., Tammer, L., Xin, B., Bakhtiari, S., Rice, J., van Eyk, C.L., Gecz, J., Mah, J.K., Atkinson, D., Cope, H., Sullivan, J.A., Douek, A.M., Colquhoun, D., Henry, J., Wlodkowic, D., Parman, Y., Candayan, A., Kocasoy-Orhan, E., Ilivitzki, A., Soudry, S., Leibu, R., Glaser, F., Sency, V., Undiagnosed Diseases Network, Ast, G., Shashi, V., Fahey, M.C., Battaloğlu, E., Jordanova, A., Meiner, V., Innes, A.M., Wang, H., Elpeleg, O., Kruer, M.C., Kaslin, J., Baris Feldman, H. (2022) Bi-allelic variants in neuronal cell adhesion molecule cause a neurodevelopmental disorder characterized by developmental delay, hypotonia, neuropathy/spasticity. American journal of human genetics. 109(3):518-532

Serrano, R.J., Lee, C., Douek, A.M., Kaslin, J., Bryson-Richardson, R.J., Sztal, T.E. (2021) Novel pre-clinical model for CDKL5 Deficiency Disorder. Disease models & mechanisms. 15(3):

Suzzi, S., Ahrendt, R., Hans, S., Semenova, S.A., Chekuru, A., Wirsching, P., Kroehne, V., Bilican, S., Sayed, S., Winkler, S., Spieß, S., Machate, A., Kaslin, J., Panula, P., Brand, M. (2021) Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain. PLoS Genetics. 17:e1009794

Andrikopoulos, N., Song, Z., Wan, X., Douek, A.M., Javed, I., Fu, C., Xing, Y., Xin, F., Li, Y., Kakinen, A., Koppel, K., Qiao, R., Whittaker, A.K., Kaslin, J., Davis, T.P., Song, Y., Ding, F., Ke, P.C. (2021) Inhibition of Amyloid Aggregation and Toxicity with Janus Iron Oxide Nanoparticles. Chemistry of materials : a publication of the American Chemical Society. 33:6484-6500

Vandestadt, C., Vanwalleghem, G.C., Khabooshan, M.A., Douek, A.M., Castillo, H.A., Li, M., Schulze, K., Don, E., Stamatis, S.A., Ratnadiwakara, M., Änkö, M.L., Scott, E.K., Kaslin, J. (2021) RNA-induced inflammation and migration of precursor neurons initiates neuronal circuit regeneration in zebrafish. Developmental Cell. 56:2364-2380.e8

Douek, A.M., Amiri Khabooshan, M., Henry, J., Stamatis, S.A., Kreuder, F., Ramm, G., Änkö, M.L., Wlodkowic, D., Kaslin, J. (2021) An Engineered sgsh Mutant Zebrafish Recapitulates Molecular and Behavioural Pathobiology of Sanfilippo Syndrome A/MPS IIIA. International Journal of Molecular Sciences. 22(11):

Douek, A.M., Klein, E.I., Kaslin, J., Currie, P.D., Ruparelia, A.A. (2021) Cellular and Molecular Characterization of the Effects of the Zebrafish Embryo Genotyper Protocol. Zebrafish. 18(1):92-95

Schwarzer, S., Asokan, N., Bludau, O., Kuscha, V., Kaslin, J., Hans, S. (2020) Neurogenesis in the inner ear: the zebrafish statoacoustic ganglion provides new neurons from a Neurod/Nestin-positive progenitor pool well into adulthood. Development (Cambridge, England). 147(7):

Hin, N., Newman, M., Kaslin, J., Douek, A.M., Lumsden, A., Nik, S.H.M., Dong, Y., Zhou, X.F., Mañucat-Tan, N.B., Ludington, A., Adelson, D.L., Pederson, S., Lardelli, M. (2020) Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2. PLoS One. 15:e0227258

Lu, Z., Douek, A.M., Rozario, A.M., Tabor, R.F., Kaslin, J., Follink, B., Teo, B.M. (2020) Bioinspired polynorepinephrine nanoparticles as an efficient vehicle for enhanced drug delivery. Journal of materials chemistry. B. 8(5):961-968

Kakinen, A., Xing, Y., Hegoda Arachchi, N., Javed, I., Feng, L., Faridi, A., Douek, A.M., Sun, Y., Kaslin, J., Davis, T.P., Higgins, M.J., Ding, F., Ke, P.C. (2019) Single-Molecular Heteroamyloidosis of Human Islet Amyloid Polypeptide. Nano Letters. 19(9):6535-6546

Walpitagama, M., Carve, M., Douek, A.M., Trestrail, C., Bai, Y., Kaslin, J., Wlodkowic, D. (2019) Additives migrating from 3D-printed plastic induce developmental toxicity and neuro-behavioural alterations in early life zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 213:105227

Lindsey, B.W., Aitken, G.E., Tang, J.K., Khabooshan, M., Douek, A.M., Vandestadt, C., Kaslin, J. (2019) Midbrain tectal stem cells display diverse regenerative capacities in zebrafish. Scientific Reports. 9:4420

Singh, A., Castillo, H.A., Brown, J., Kaslin, J., Dwyer, K.M., Gibert, Y. (2019) High glucose levels affect retinal patterning during zebrafish embryogenesis. Scientific Reports. 9:4121

Hamimi, M., Khabooshan, M., Castillo, H.A., Kaslin, J. (2018) Fluorescently Labeled TracrRNA Improves Work Flow and Facilitates Successful Genome Editing in Zebrafish. Zebrafish. 16(1):135-137

Goldshmit, Y., Tang, J.K.K.Y., Siegel, A.L., Nguyen, P.D., Kaslin, J., Currie, P.D., Jusuf, P.R. (2018) Different Fgfs have distinct roles in regulating neurogenesis after spinal cord injury in zebrafish. Neural Development. 13:24

Friedrich, T., Douek, A.M., Vandestadt, C., Wlodkowic, D., Kaslin, J. (2018) A Modular Millifluidic Homeostatic Imaging Plate for Imaging of Larval Zebrafish. Zebrafish. 16(1):37-46

Lindsey, B.W., Hall, Z.J., Heuzé, A., Joly, J.S., Tropepe, V., Kaslin, J. (2018) The role of neuro-epithelial-like and radial-glial stem and progenitor cells in development, plasticity, and repair. Prog. Neurobiol.. 170:99-114

Mohd Fuad, N., Carve, M., Kaslin, J., Wlodkowic, D. (2018) Characterization of 3D-Printed Moulds for Soft Lithography of Millifluidic Devices. Micromachines. 9(3)

Huang, Y., Cartlidge, R., Walpitagama, M., Kaslin, J., Campana, O., Wlodkowic, D. (2018) Unsuitable use of DMSO for assessing behavioral endpoints in aquatic model species. The Science of the total environment. 615:107-114

Lindsey, B.W., Douek, A.M., Loosli, F., Kaslin, J. (2018) A Whole Brain Staining, Embedding, and Clearing Pipeline for Adult Zebrafish to Visualize Cell Proliferation and Morphology in 3-Dimensions. Frontiers in neuroscience. 11:750

Wyett, G., Gibert, Y., Ellis, M., Castillo, H.A., Kaslin, J., Aston-Mourney, K. (2017) Metformin, beta-cell development, and novel processes following beta-cell ablation in zebrafish. Endocrine. 59(2):419-425

Bower, N.I., Koltowska, K., Pichol-Thievend, C., Virshup, I., Paterson, S., Lagendijk, A.K., Wang, W., Lindsey, B.W., Bent, S.J., Baek, S., Rondon-Galeano, M., Hurley, D.G., Mochizuki, N., Simons, C., Francois, M., Wells, C.A., Kaslin, J., Hogan, B.M. (2017) Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish. Nature Neuroscience. 20(6):774-783

Kaslin, J., Kroehne, V., Ganz, J., Hans, S., Brand, M. (2017) Distinct roles of neuroepithelial-like and radial glia-like progenitor cells in cerebellar regeneration. Development (Cambridge, England). 144(8):1462-1471

Lindsey, B.W., Kaslin, J. (2017) Optical Projection Tomography as a Novel Method to Visualize and Quantitate Whole-Brain Patterns of Cell Proliferation in the Adult Zebrafish Brain. Zebrafish. 14(6):574-577

Frisca, F., Colquhoun, D., Goldshmit, Y., Änkö, M.L., Pébay, A., Kaslin, J. (2016) Role of ectonucleotide pyrophosphatase/phosphodiesterase 2 in the midline axis formation of zebrafish. Scientific Reports. 6:37678

Zhu, F., Wigh, A., Friedrich, T., Devaux, A., Bony, S., Nugegoda, D., Kaslin, J., Wlodkowic, D. (2015) Automated Lab-on-a-Chip Technology for Fish Embryo Toxicity Tests Performed under Continuous Microperfusion (μFET). Environmental science & technology. 49(24):14570-8

Zhu, F., Skommer, J., Macdonald, N.P., Friedrich, T., Kaslin, J., Wlodkowic, D. (2015) Three-dimensional printed millifluidic devices for zebrafish embryo tests. Biomicrofluidics. 9:046502

Goldshmit, Y., Frisca, F., Kaslin, J., Pinto, A.R., Tang, J.K., Pébay, A., Pinkas-Kramarski, R., Currie, P.D. (2015) Decreased anti-regenerative effects after spinal cord injury in spry4-/- mice. Neuroscience. 287:104-12

Ganz, J., Kroehne, V., Freudenreich, D., Machate, A., Geffarth, M., Braasch, I., Kaslin, J., Brand, M. (2014) Subdivisions of the adult zebrafish pallium based on molecular marker analysis. F1000Research. 3:308

Lindsey, B.W., Di Donato, S., Kaslin, J., Tropepe, V. (2014) Sensory-specific modulation of adult neurogenesis in sensory structures is associated with the type of stem cell present in the neurogenic niche of the zebrafish brain. The European journal of neuroscience. 40(11):3591-607

Weber, A., Hochmann, S., Cimalla, P., Gärtner, M., Kuscha, V., Hans, S., Geffarth, M., Kaslin, J., Koch, E., and Brand, M. (2013) Characterization of light lesion paradigms and optical coherence tomography as tools to study adult retina regeneration in zebrafish. PLoS One. 8(11):e80483

de Oliveira-Carlos, V., Ganz, J., Hans, S., Kaslin, J., and Brand, M. (2013) Notch receptor expression in neurogenic regions of the adult zebrafish brain. PLoS One. 8(9):e73384

Kizil, C., Iltzsche, A., Kaslin, J., and Brand, M. (2013) Micromanipulation of gene expression in the adult zebrafish brain using cerebroventricular microinjection of morpholino oligonucleotides. Journal of visualized experiments : JoVE. (75):e50415

Kaslin, J., Kroehne, V., Benato, F., Argenton, F., and Brand, M. (2013) Development and specification of cerebellar stem and progenitor cells in zebrafish: from embryo to adult. Neural Development. 8(1):9

Kizil, C., Kyritsis, N., Dudczig, S., Kroehne, V., Freudenreich, D., Kaslin, J., and Brand, M. (2012) Regenerative Neurogenesis from Neural Progenitor Cells Requires Injury-Induced Expression of Gata3. Developmental Cell. 23(6):1230-1237

Kyritsis, N., Kizil, C., Zocher, S., Kroehne, V., Kaslin, J., Freudenreich, D., Iltzsche, A., and Brand, M. (2012) Acute Inflammation Initiates the Regenerative Response in the Adult Zebrafish Brain. Science (New York, N.Y.). 338(6112):1353-1356

Kizil, C., Kaslin, J., Kroehne, V., and Brand, M. (2012) Adult neurogenesis and brain regeneration in zebrafish. Developmental Neurobiology. 72(3):429-461

Ganz, J., Kaslin, J., Freudenreich, D., Machate, A., Geffarth, M., and Brand, M. (2012) Subdivisions of the adult zebrafish subpallium by molecular marker analysis. The Journal of comparative neurology. 520(3):633-55

Hochmann, S., Kaslin, J., Hans, S., Weber, A., Machate, A., Geffarth, M., Funk, R.H., and Brand, M. (2012) Fgf Signaling is Required for Photoreceptor Maintenance in the Adult Zebrafish Retina. PLoS One. 7(1):e30365

Kroehne, V., Freudenreich, D., Hans, S., Kaslin, J., and Brand, M. (2011) Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors. Development (Cambridge, England). 138(22):4831-4841

Gutnick, A., Blechman, J., Kaslin, J., Herwig, L., Belting, H.G., Affolter, M., Bonkowsky, J.L., and Levkowitz, G. (2011) The hypothalamic neuropeptide oxytocin is required for formation of the neurovascular interface of the pituitary. Developmental Cell. 21(4):642-654

Hans, S., Freudenreich, D., Geffarth, M., Kaslin, J., Machate, A., and Brand, M. (2011) Generation of a non-leaky heat shock-inducible Cre line for conditional Cre/lox strategies in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(1):108-115

Ganz, J., Kaslin, J., Hochmann, S., Freudenreich, D., and Brand, M. (2010) Heterogeneity and Fgf dependence of adult neural progenitors in the zebrafish telencephalon. Glia. 58(11):1345-1363

Kaslin, J., Ganz, J., Geffarth, M., Grandel, H., Hans, S., and Brand, M. (2009) Stem cells in the adult zebrafish cerebellum: initiation and maintenance of a novel stem cell niche. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(19):6142-6153

Sallinen, V., Sundvik, M., Reenilä, I., Peitsaro, N., Khrustalyov, D., Anichtchik, O., Toleikyte, G., Kaslin, J., and Panula, P. (2009) Hyperserotonergic phenotype after monoamine oxidase inhibition in larval zebrafish. Journal of neurochemistry. 109(2):403-415

Hans, S., Kaslin, J., Freudenreich, D., and Brand, M. (2009) Temporally-controlled site-specific recombination in zebrafish. PLoS One. 4(2):e4640

Peitsaro, N., Sundvik, M., Anichtchik, O.V., Kaslin, J., and Panula, P. (2007) Identification of zebrafish histamine H(1), H(2) and H(3) receptors and effects of histaminergic ligands on behavior. Biochemical pharmacology. 73(8):1205-1214

Grandel, H., Kaslin, J., Ganz, J., Wenzel, I., and Brand, M. (2006) Neural stem cells and neurogenesis in the adult zebrafish brain: Origin, proliferation dynamics, migration and cell fate. Developmental Biology. 295(1):263-277

Kaslin, J., Nystedt, J.M., Ostergard, M., Peitsaro, N., and Panula, P. (2004) The orexin/hypocretin system in zebrafish is connected to the aminergic and cholinergic systems. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24(11):2678-2689

Anichtchik, O.V., Kaslin, J., Peitsaro, N., Scheinin, M., and Panula, P. (2004) Neurochemical and behavioural changes in zebrafish Danio rerio after systemic administration of 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Journal of neurochemistry. 88(2):443-453

Kaslin, K.V.M. (2004) The aminergic and cholinergic neurotransmitter systems in the zebrafish brain. Thesis.

Peitsaro, N., Kaslin, J., Anichtchik, O.V., and Panula, P. (2003) Modulation of the histaminergic system and behaviour by alpha-fluoromethylhistidine in zebrafish. Journal of neurochemistry. 86(2):432-441

Kaslin, J. and Panula, P. (2001) Comparative anatomy of the histaminergic and other aminergic systems in zebrafish (Danio rerio). The Journal of comparative neurology. 440(4):342-377

Panula, P., Karlstedt, K., Sallmen, T., Peitsaro, N., Kaslin, J., Michelsen, K.A., Anichtchik, O., Kukko-Lukjanov, T., and Lintunen, M. (2000) The histaminergic system in the brain: structural characteristics and changes in hibernation. Journal of chemical neuroanatomy. 18(1-2):65-74

Eriksson, K.S., Peitsaro, N., Karlstedt, K., Kaslin, J., and Panula, P. (1998) Development of the histaminergic neurons and expression of histidine decarboxylase mRNA in the zebrafish brain in the absence of all peripheral histaminergic systems. The European journal of neuroscience. 10:3799-3812

Eriksson, K.S., Kaslin, J., and Panula, P. (1996) Development of the histaminergic nervous system in the zebrafish brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 51:99