ZFIN ID: ZDB-LAB-181210-1
Campàs Lab
PI/Director: Campas, Otger
Contact Person: Campas, Otger
Email: otger.campas@tu-dresden.de
URL:
Address: Physics of Life Excellence Cluster, TU Dresden & University of California, Santa Barbara
Country: Germany
Phone:
Fax:
Line Designation: None assigned


GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available


STATEMENT OF RESEARCH INTERESTS
The Campàs Lab studies tissue/organ morphogenesis in zebrafish from an interdisciplinary perspective, with the overreaching goal of quantitatively connecting the physical/mechanical processes responsible for sculpting biological structures to the genetic and molecular processes that orchestrate their formation. Our research is focused on understanding (1) the physical mechanisms underlying tissue/organ development, (2) the role of mechanics in controlling cell behavior in vivo, (3) the interplay between biochemical signaling and tissue mechanics in embryogenesis and (4) the physics of active multicellular systems. Please check our website to learn more about our research interests.


LAB MEMBERS
Kim, Sangwoo Post-Doc Pochitaloff, Marie Post-Doc Stooke-Vaughan, Georgina Post-Doc
Vian, Antoine Post-Doc Yen, Shou-Ting Post-Doc Banavar, Samhita Graduate Student
Shelton, Elijah Graduate Student Froeb, Claudia Technical Staff Liu, Yucen Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Vian, A., Pochitaloff, M., Yen, S.T., Kim, S., Pollock, J., Liu, Y., Sletten, E.M., Campàs, O. (2023) In situ quantification of osmotic pressure within living embryonic tissues. Nature communications. 14:70237023
Mongera, A., Pochitaloff, M., Gustafson, H.J., Stooke-Vaughan, G.A., Rowghanian, P., Kim, S., Campàs, O. (2022) Mechanics of the cellular microenvironment as probed by cells in vivo during zebrafish presomitic mesoderm differentiation. Nature Materials. 22(1):135-143
Kim, S., Pochitaloff, M., Stooke-Vaughan, G.A., Campàs, O. (2021) Embryonic Tissues as Active Foams. Nature physics. 17:859-866
Banavar, S.P., Carn, E.K., Rowghanian, P., Stooke-Vaughan, G., Kim, S., Campàs, O. (2021) Mechanical control of tissue shape and morphogenetic flows during vertebrate body axis elongation. Scientific Reports. 11:8591
Lim, I., Vian, A., van de Wouw, H., Day, R.A., Gomez, C., Liu, Y., Rheingold, A.L., Campas, O., Sletten, E.M. (2020) Fluorous soluble cyanine dyes for visualizing perfluorocarbons in living systems. Journal of the American Chemical Society. 142(37):16072-16081
Yen, S.T., Trimmer, K.A., Aboul-Fettouh, N., Mullen, R.D., Culver, J.C., Dickinson, M.E., Behringer, R.R., Eisenhoffer, G.T. (2020) CreLite: An Optogenetically Controlled Cre/loxP System Using Red Light. Developmental Dynamics : an official publication of the American Association of Anatomists. 249(11):1394-1403
Banavar, S.P., Gomez, C., Trogdon, M., Petzold, L.R., Yi, T.M., and Campàs, O. (2019) Mechanical feedback coordinates cell wall expansion and assembly in yeast mating morphogenesis. PLoS Computational Biology. 14(1):e1005940
Mongera, A., Rowghanian, P., Gustafson, H.J., Shelton, E., Kealhofer, D.A., Carn, E.K., Serwane, F., Lucio, A.A., Giammona, J., and Campàs, O. (2018) A fluid-to-solid jamming transition underlies vertebrate body axis elongation.. Nature. 561:401-405
Stooke-Vaughan, G.A., and Campàs, O. (2018) Physical control of tissue morphogenesis across scales.. Current opinion in genetics & development. 51:111-119
Serwane, F., Mongera, A., Rowghanian, P., Kealhofer, D.A., Lucio, A.A., Hockenbery, Z.M., Campàs, O. (2017) In vivo quantification of spatially varying mechanical properties in developing tissues. Nature Methods. 14(2):181-186
Campàs, O. (2016) A toolbox to explore the mechanics of living embryonic tissues. Seminars in cell & developmental biology. 55:119-30
Stooke-Vaughan, G.A., Obholzer, N.D., Baxendale, S., Megason, S.G., Whitfield, T.T. (2015) Otolith tethering in the zebrafish otic vesicle requires Otogelin and α-Tectorin. Development (Cambridge, England). 142(6):1137-45
Stooke-Vaughan, G.A., Huang, P., Hammond, K.L., Schier, A.F., and Whitfield, T.T. (2012) The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle. Development (Cambridge, England). 139(10):1777-1787
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