ZFIN Lab: Liu Dong Lab

ZFIN ID: ZDB-LAB-160503-1

Liu Dong Lab

PI/Director:	Liu, Dong
Contact Person:	Liu, Dong
Email:	liudongtom@gmail.com
URL:	http://nrl.ntu.edu.cn/sjkxx/xsdw/content/7dd91afc-a1c6-47e9-b546-7e77b36d86bf.html
Address:	Jiangsu Key Laboratory of Neuroregeneration, Nantong University Room 208, Building 8 19# Qixiu Road, Nantong, Jiangsu Province, China 226001
Country:	China
Phone:	+86-513-85051593
Fax:	+86-513-85511585
Line Designation:	ntu

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 9 genomic features

STATEMENT OF RESEARCH INTERESTS

To identify novel regulators of angiogenesis during embryonic development and tissue regeneration.

LAB MEMBERS

Gao, Yu Graduate Student	Qi, Jialing Graduate Student	Qin, Yinyin Graduate Student
Yin, Zhenhua Graduate Student	Yuan, Wei Graduate Student	Gong, Jie Research Staff
Shi, Yunwei Research Staff	Wang, Xin Research Staff	Yang, Jinxian Research Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Sheng, J., Jiang, B., Shi, R., Shi, L., Liu, D. (2022) Sema4C Is Required for Vascular and Primary Motor Neuronal Patterning in Zebrafish. Cells. 11(16)

Wang, X., Ge, X., Qin, Y., Liu, D., Chen, C. (2022) Ifi30 Is Required for Sprouting Angiogenesis During Caudal Vein Plexus Formation in Zebrafish. Frontiers in Physiology. 13:919579

Qian, F., Wei, G., Gao, Y., Wang, X., Gong, J., Guo, C., Wang, X., Zhang, X., Zhao, J., Wang, C., Xu, M., Hu, Y., Yin, G., Kang, J., Chai, R., Xie, G., Liu, D. (2022) Single-cell RNA-sequencing of zebrafish hair cells reveals novel genes potentially involved in hearing loss. Cellular and molecular life sciences : CMLS. 79:385

Duan, X., Shi, Y., Zhao, S., Yao, L., Sheng, J., Liu, D. (2022) Foxc1a regulates zebrafish vascular integrity and brain vascular development through targeting amotl2a and ctnnb1. Microvascular Research. 143:104400

Zhao, J., Wei, G., Zhu, J., Liu, D., Qin, B. (2022) Expression analysis of nel during zebrafish embryonic development. Gene expression patterns : GEP. 45:119258

Lu, Y., Tang, D., Zheng, Z., Wang, X., Zuo, N., Yan, R., Wu, C., Ma, J., Wang, C., Xu, H., He, Y., Liu, D., Liu, S. (2022) Cingulin b Is Required for Zebrafish Lateral Line Development Through Regulation of Mitogen-Activated Protein Kinase and Cellular Senescence Signaling Pathways. Frontiers in molecular neuroscience. 15:844668

Sheng, J., Xu, J., Geng, K., Liu, D. (2022) Sema6D Regulates Zebrafish Vascular Patterning and Motor Neuronal Axon Growth in Spinal Cord. Frontiers in molecular neuroscience. 15:854556

Sheng, J., Gong, J., Shi, Y., Wang, X., Liu, D. (2022) MicroRNA-22 coordinates vascular and motor neuronal pathfinding via sema4 during zebrafish development. Open Biology. 12:210315

Zheng, Y.Q., Suo, G.H., Liu, D., Li, H.Y., Wu, Y.J., Ni, H. (2022) Nexmifa Regulates Axon Morphogenesis in Motor Neurons in Zebrafish. Frontiers in molecular neuroscience. 15:848257

Wei, G., Zhang, X., Cai, C., Sheng, J., Xu, M., Wang, C., Gu, Q., Guo, C., Chen, F., Liu, D., Qian, F. (2022) Dual-Specificity Phosphatase 14 Regulates Zebrafish Hair Cell Formation Through Activation of p38 Signaling Pathway. Frontiers in Cellular Neuroscience. 16:840143

Zheng, S., Tang, D., Wang, X., Liu, C., Zuo, N., Yan, R., Wu, C., Ma, J., Wang, C., Xu, H., He, Y., Liu, D., Liu, S. (2022) Kif15 Is Required in the Development of Auditory System Using Zebrafish as a Model. Frontiers in molecular neuroscience. 15:844568

Qian, P., Kang, J., Liu, D., Xie, G. (2022) Single Cell Transcriptome Sequencing of Zebrafish Testis Revealed Novel Spermatogenesis Marker Genes and Stronger Leydig-Germ Cell Paracrine Interactions. Frontiers in genetics. 13:851719

Wang, S., Qin, Y., Sheng, J., Duan, X., Shen, L., Liu, D. (2022) Aquaporin 8ab is required in zebrafish embryonic intestine development. Acta biochimica et biophysica Sinica. 54:1-9

Xu, G., Huang, Z., Sheng, J., Gao, X., Xin, W., Garcia, J.Q., Wei, G., Liu, D., Gong, J. (2021) FGF binding protein 3 is required for spinal cord motor neuron development and regeneration in zebrafish. Experimental neurology. 348:113944

Gong, J., Qian, P., Hu, Y., Guo, C., Wei, G., Wang, C., Cai, C., Wang, H., Liu, D. (2021) Claudin h Is Essential for Hair Cell Morphogenesis and Auditory Function in Zebrafish. Frontiers in cell and developmental biology. 9:663995

Zhang, Y., Wang, Y., Yao, X., Wang, C., Chen, F., Liu, D., Shao, M., Xu, Z. (2020) Rbm24a Is Necessary for Hair Cell Development Through Regulating mRNA Stability in Zebrafish. Frontiers in cell and developmental biology. 8:604026

Shen, D., Chen, J., Liu, D., Shen, M., Wang, X., Wu, Y., Ke, S., Macdonald, R.L., Zhang, Q. (2020) The GABRG2 F343L allele causes spontaneous seizures in a novel transgenic zebrafish model that can be treated with suberanilohydroxamic acid (SAHA). Annals of translational medicine. 8:1560

Shi, L., Chen, C., Yin, Z., Wei, G., Xie, G., Liu, D. (2020) Systematic profiling of early regulators during tissue regeneration using zebrafish model. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 29(1):189-195

Gong, J., Hu, S., Huang, Z., Hu, Y., Wang, X., Zhao, J., Qian, P., Wang, C., Sheng, J., Lu, X., Wei, G., Liu, D. (2020) The Requirement of Sox2 for the Spinal Cord Motor Neuron Development of Zebrafish. Frontiers in molecular neuroscience. 13:34

Zhang, H., Gao, Y., Qian, P., Dong, Z., Hao, W., Liu, D., Duan, X. (2019) Expression analysis of Rab11 during zebrafish embryonic development. BMC Developmental Biology. 19:25

Gao, Y., Liu, Z., Jia, D., Hu, Q., Li, L., Tang, R., Li, D. (2019) Acute microcystin-LR exposure interfere thyroid hormones homeostasis in adult zebrafish (Danio rerio). Chemosphere. 243:125258

Zhang, Z., Hou, H., Yu, S., Zhou, C., Zhang, X., Li, N., Zhang, S., Song, K., Lu, Y., Liu, D., Lu, H., Xu, H. (2019) Inflammation-induced mammalian target of rapamycin signaling is essential for retina regeneration. Glia. 68(1):111-127

Shi, Y., Wang, X., Shi, Y., Zhang, J., Zhao, S., Yin, Z., Xu, G., Duan, X., Guo, Z., Liang, X., Liu, D. (2019) Two Compounds Isolated From Ganglioside GM1 Promote Angiogenesis in Zebrafish. Journal of Cardiovascular Pharmacology. 74:71-79

Liao, S., Han, L., Zheng, X., Wang, X., Zhang, P., Wu, J., Liu, R., Fu, Y., Sun, J., Kang, X., Liu, K., Fan, T., Li, S., Zheng, X. (2019) Tanshinol borneol ester (DBZ), a novel synthetic small molecule angiogenesis stimulator inspired by botanical formulations for angina pectoris. British journal of pharmacology. 176(17):3143-3160

Qin, Y., Wang, S., Duan, X., Liu, D. (2019) Expression analysis of the aquaporins during zebrafish embryonic development. Gene expression patterns : GEP. 32:38-43

Zhang, K., Zhang, H., Zhou, H., Crookes, D., Li, L., Shao, Y., Liu, D. (2019) Zebrafish Embryo Vessel Segmentation Using a Novel Dual ResUNet Model. Computational intelligence and neuroscience. 2019:8214975

Shi, Y., Duan, X., Xu, G., Wang, X., Wei, G., Dong, S., Xie, G., Liu, D. (2019) A ribosomal DNA-hosted microRNA regulates zebrafish embryonic angiogenesis. Angiogenesis. 22(2):211-221

Dong, Z., Wu, S., Zhu, C., Wang, X., Li, Y., Chen, X., Liu, D., Qiang, L., Baas, P.W., Liu, M. (2018) CRISPR/Cas9-mediated kif15 mutations accelerate axonal outgrowth during neuronal development and regeneration in zebrafish. Traffic (Copenhagen, Denmark). 20(1):71-81

Gong, J., Chai, L., Xu, G., Ni, Y., Liu, D. (2018) The expression of natriuretic peptide receptors in developing zebrafish embryos. Gene expression patterns : GEP. 29:65-71

Liu, Z.Z., Zhu, J., Wang, C.L., Wang, X., Han, Y.Y., Liu, L.Y., Xu, H.A. (2018) CRMP2 and CRMP4 Are Differentially Required for Axon Guidance and Growth in Zebrafish Retinal Neurons. Neural Plasticity. 2018:8791304

Bao, L., You, B., Shi, S., Shan, Y., Zhang, Q., Yue, H., Zhang, J., Zhang, W., Shi, Y., Liu, Y., Wang, X., Liu, D., You, Y. (2018) Metastasis-associated miR-23a from nasopharyngeal carcinoma-derived exosomes mediates angiogenesis by repressing a novel target gene TSGA10. Oncogene. 37(21):2873-2889

Chen, Z., Shao, X.Y., Wang, C., Hua, M.H., Wang, C.N., Wang, X., Wang, Q.J., Yao, J.Y., Fan, Y.H., Qin, Y.W. (2018) Mycobacterium marinum Infection in Zebrafish and Microglia Imitates the Early Stage of Tuberculous Meningitis. Journal of molecular neuroscience : MN. 64(2):321-330

Gao, Y., Liu, J., Wang, X., Liu, D. (2017) [Genetic manipulation in zebrafish]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 33:1674-1692

Jin, D., Zhu, D., Fang, Y., Chen, Y., Yu, G., Pan, W., Liu, D., Li, F., Zhong, T.P. (2017) Vegfa signaling regulates diverse artery/vein formation in vertebrate vasculatures. Journal of genetics and genomics = Yi chuan xue bao. 44(10):483-492

Gong, J., Wang, X., Zhu, C., Dong, X., Zhang, Q., Wang, X., Duan, X., Qian, F., Shi, Y., Gao, Y., Zhao, Q., Chai, R., Liu, D. (2017) Insm1a Regulates Motor Neuron Development in Zebrafish. Frontiers in molecular neuroscience. 10:274

He, Y., Lu, X., Qian, F., Liu, D., Chai, R., Li, H. (2017) Insm1a Is Required for Zebrafish Posterior Lateral Line Development.. Frontiers in molecular neuroscience. 10:241

Wang, F., Liu, D., Zhang, R.R., Yu, L.W., Zhao, J.Y., Yang, X.Y., Jiang, S.S., Ma, D., Qiao, B., Zhang, F., Jin, L., Gui, Y.H., Wang, H.Y. (2017) A TBX5 3'UTR variant increases the risk of congenital heart disease in the Han Chinese population. Cell discovery. 3:17026

Zhang, J., Qi, J., Wu, S., Peng, L., Shi, Y., Yang, J., Yin, Z., Gao, Y., Wang, C., Gong, J., Zhang, H., Zhang, J., Liu, D. (2017) Fatty Acid Binding Protein 11a Is Required for Brain Vessel Integrity in Zebrafish. Frontiers in Physiology. 8:214

Li, J.M., Li, L.Y., Qin, X., Ning, L.J., Lu, D.L., Li, D.L., Zhang, M.L., Wang, X., Du, Z.Y. (2017) Corrigendum: Systemic regulation of L-carnitine in nutritional metabolism in zebrafish, Danio rerio. Scientific Reports. 7:44970

Zhang, J.J., Wang, X., Liu, D. (2017) [Natriuretic peptide precursor C coding gene contributes to zebrafish angiogenesis]. Sheng li xue bao : [Acta physiologica Sinica]. 69:11-16

Lv, F., Zhu, C., Yan, X., Wang, X., Liu, D. (2017) Generation of a mef2aa:EGFP transgenic zebrafish line that expresses EGFP in muscle cells. Fish physiology and biochemistry. 43(1):287-294

Mu, Z., Zhang, S., He, C., Hou, H., Liu, D., Hu, N., Xu, H. (2017) Expression of SoxC Transcription Factors during Zebrafish Retinal and Optic Nerve Regeneration. Neuroscience Bulletin. 33(1):53-61

Li, J.M., Li, L.Y., Qin, X., Ning, L.J., Lu, D.L., Li, D.L., Zhang, M.L., Wang, X., Du, Z.Y. (2017) Systemic regulation of L-carnitine in nutritional metabolism in zebrafish, Danio rerio. Scientific Reports. 7:40815

Lin, Q., Fan, S., Zhang, Y., Xu, M., Zhang, H., Yang, Y., Lee, A.P., Woltering, J.M., Ravi, V., Gunter, H.M., Luo, W., Gao, Z., Lim, Z.W., Qin, G., Schneider, R.F., Wang, X., Xiong, P., Li, G., Wang, K., Min, J., Zhang, C., Qiu, Y., Bai, J., He, W., Bian, C., Zhang, X., Shan, D., Qu, H., Sun, Y., Gao, Q., Huang, L., Shi, Q., Meyer, A., Venkatesh, B. (2016) The seahorse genome and the evolution of its specialized morphology. Nature. 540:395-399

Qi, J., Dong, Z., Shi, Y., Wang, X., Qin, Y., Wang, Y., Liu, D. (2016) NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish. Cell Research. 26(12):1349-1352

Wang, X., Yuan, W., Wang, X., Qi, J., Qin, Y., Shi, Y., Zhang, J., Gong, J., Dong, Z., Liu, X., Sun, C., Chai, R., Le Noble, F., Liu, D. (2016) The somite-secreted factor Maeg promotes zebrafish embryonic angiogenesis. Oncotarget. 7(47):77749-77763

Shi, Y.W., Yuan, W., Wang, X., Gong, J., Zhu, S.X., Chai, L.L., Qi, J.L., Qin, Y.Y., Gao, Y., Zhou, Y.L., Fan, X.L., Ji, C.Y., Wu, J.Y., Wang, Z.W., Liu, D. (2016) Combretastatin A-4 efficiently inhibits angiogenesis and induces neuronal apoptosis in zebrafish. Scientific Reports. 6:30189

Wang, X., Ling, C.C., Li, L., Qin, Y., Qi, J., Liu, X., You, B., Shi, Y., Zhang, J., Jiang, Q., Xu, H., Sun, C., You, Y., Chai, R., Liu, D. (2016) MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis. Cardiovascular research. 110(1):140-50