ZFIN ID: ZDB-LAB-140806-1
Zebrafish Aquaculture Core (ZAC) facility
PI/Director: Ortwine, Michelle
Contact Person: Ortwine, Michelle
Email: ortwine@unc.edu
URL:
Address: 101 Mason Farm Rd Glaxo Research Bld 024 Chapel Hill, NC 27599-7507
Country: United States
Phone: 919-843-5370
Fax:
Line Designation: None assigned


GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Bai, Xue Post-Doc Chrispell, Jared Post-Doc Li, Xi Post-Doc
Mouillesseaux, Kevin Post-Doc Chong, Diana Research Staff Mangum, Kevin Dale Research Staff
Ratliff, Lyndsay Research Staff Samsa, Leigh Ann Research Staff Xiong, Yubin Research Staff
Waugh, Trent


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Chrispell, J.D., Xiong, Y., Weiss, E.R. (2022) Grk7 but not Grk1 undergoes cAMP-dependent phosphorylation in zebrafish cone photoreceptors and mediates cone photoresponse recovery to elevated cAMP. The Journal of biological chemistry. 298(12):102636
Battista, N.A., Douglas, D.R., Lane, A.N., Samsa, L.A., Liu, J., Miller, L.A. (2019) Vortex Dynamics in Trabeculated Embryonic Ventricles. Journal of cardiovascular development and disease. 6(1)
Chrispell, J.D., Dong, E., Osawa, S., Liu, J., Cameron, D.J., Weiss, E.R. (2018) Grk1b and Grk7a Both Contribute to the Recovery of the Isolated Cone Photoresponse in Larval Zebrafish. Investigative ophthalmology & visual science. 59:5116-5124
Wylie, L.A., Mouillesseaux, K.P., Chong, D.C., Bautch, V.L. (2018) Developmental SMAD6 Loss Leads to Blood Vessel Hemorrhage and Disrupted Endothelial Cell Junctions. Developmental Biology. 442(2):199-209
Fleming, N.D., Samsa, L.A., Hassel, D., Qian, L., Liu, J. (2018) Rapamycin attenuates pathological hypertrophy caused by an absence of trabecular formation. Scientific Reports. 8:8584
Brown, D., Samsa, L.A., Ito, C., Ma, H., Batres, K., Arnaout, R., Qian, L., Liu, J. (2017) Neuregulin-1 is essential for nerve plexus formation during cardiac maturation. Journal of Cellular and Molecular Medicine. 22(3):2007-2017
Haskell, G.T., Jensen, B.C., Samsa, L.A., Marchuk, D., Huang, W., Skrzynia, C., Tilley, C., Seifert, B.A., Rivera-Muñoz, E.A., Koller, B., Wilhelmsen, K.C., Liu, J., Alhosaini, H., Weck, K.E., Evans, J.P., Berg, J.S. (2017) Whole Exome Sequencing Identifies Truncating Variants in Nuclear Envelope Genes in Patients With Cardiovascular Disease. Circulation. Cardiovascular genetics. 10(3):e001443
Samsa, L.A., Ito, C.E., Brown, D.R., Qian, L., Liu, J. (2016) IgG-Containing Isoforms of Neuregulin-1 Are Dispensable for Cardiac Trabeculation in Zebrafish. PLoS One. 11:e0166734
Mouillesseaux, K.P., Wiley, D.S., Saunders, L.M., Wylie, L.A., Kushner, E.J., Chong, D.C., Citrin, K.M., Barber, A.T., Park, Y., Kim, J.D., Samsa, L.A., Kim, J., Liu, J., Jin, S.W., Bautch, V.L. (2016) Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6.. Nature communications. 7:13247
Brown, D.R., Samsa, L.A., Qian, L., Liu, J. (2016) Advances in the Study of Heart Development and Disease Using Zebrafish. Journal of cardiovascular development and disease. 3(2)
Samsa, L.A., Fleming, N., Magness, S., Qian, L., Liu, J. (2016) Isolation and Characterization of Single Cells from Zebrafish Embryos. Journal of visualized experiments : JoVE. (109)
Samsa, L.A., Givens, C., Tzima, E., Stainier, D.Y., Qian, L., Liu, J. (2015) Cardiac contraction activates endocardial Notch signaling to modulate chamber maturation in zebrafish. Development (Cambridge, England). 142:4080-91
Chrispell, J.D., Rebrik, T.I., Weiss, E.R. (2015) Electroretinogram Analysis of the Visual Response in Zebrafish Larvae. Journal of visualized experiments : JoVE. (97)
Waugh, T.A., Horstick, E., Hur, J., Jackson, S.W., Davidson, A.E., Li, X., Dowling, J.J. (2014) Fluoxetine prevents dystrophic changes in a zebrafish model of Duchenne muscular dystrophy. Human molecular genetics. 23(17):4651-62
Monte, E., Mouillesseaux, K., Chen, H., Kimball, T., Ren, S., Wang, Y., Chen, J.N., Vondriska, T.M., and Franklin, S. (2013) Systems Proteomics of Cardiac Chromatin Identifies Nucleolin as a Regulator of Growth and Cellular Plasticity in Cardiomyocytes. American journal of physiology. Heart and circulatory physiology. 305(11):H1624-38
Chappell, J.C., Mouillesseaux, K.P., and Bautch, V.L. (2013) Flt-1 (Vascular Endothelial Growth Factor Receptor-1) Is Essential for the Vascular Endothelial Growth Factor-Notch Feedback Loop During Angiogenesis. Arterioscler. Thromb. Vasc. Biol.. 33(8):1952-9
Samsa, L.A., Yang, B., Liu, J. (2013) Embryonic cardiac chamber maturation: Trabeculation, conduction, and cardiomyocyte proliferation.. American journal of medical genetics. Part C, Seminars in medical genetics. 163C(3):157-68
Telfer, W.R., Nelson, D.D., Waugh, T., Brooks, S.V., and Dowling, J.J. (2012) neb: a zebrafish model of nemaline myopathy due to nebulin mutation. Disease models & mechanisms. 5(3):389-396