ZFIN ID: ZDB-LAB-130319-1
Knaut Lab
PI/Director: Knaut, Holger
Contact Person: Chan, Dolly
Email: Dolly.Chan@med.nyu.edu
Address: Developmental Genetics Program Skirball Institute of Biomolecular Medicine New York University School of Medicine 540 First Avenue 4th Floor, Lab 15 New York, NY 10016-6497
Country: United States
Phone: 212-263-7595
Fax: 2122637760
Line Designation: sk

Show all 38 genomic features


Venkiteswaran, Gayatri Post-Doc Lewellis, Stephen Graduate Student Nagelberg, Danielle Graduate Student
Wang, John Graduate Student Fuentes, Fernando Technical Staff Chan, Dolly Administrative Staff

Levic, D.S., Yamaguchi, N., Wang, S., Knaut, H., Bagnat, M. (2021) Knock-in tagging in zebrafish facilitated by insertion into non-coding regions. Development (Cambridge, England). 148(19):
Kinney, B.A., Al Anber, A., Row, R.H., Tseng, Y.J., Weidmann, M.D., Knaut, H., Martin, B.L. (2020) Sox2 and Canonical Wnt Signaling Interact to Activate a Developmental Checkpoint Coordinating Morphogenesis with Mesoderm Fate Acquisition. Cell Reports. 33:108311
Tsai, T.Y., Sikora, M., Xia, P., Colak-Champollion, T., Knaut, H., Heisenberg, C.P., Megason, S.G. (2020) An adhesion code ensures robust pattern formation during tissue morphogenesis. Science (New York, N.Y.). 370:113-116
Lau, S., Feitzinger, A., Venkiteswaran, G., Wang, J., Lewellis, S.W., Koplinski, C.A., Peterson, F.C., Volkman, B.F., Meier-Schellersheim, M., Knaut, H. (2020) A negative-feedback loop maintains optimal chemokine concentrations for directional cell migration. Nature cell biology. 22(3):266-273
Colak-Champollion, T., Lan, L., Jadhav, A.R., Yamaguchi, N., Venkiteswaran, G., Patel, H., Cammer, M., Meier-Schellersheim, M., Knaut, H. (2019) Cadherin-Mediated Cell Coupling Coordinates Chemokine Sensing across Collectively Migrating Cells. Current biology : CB. 29:2570-2579.e7
Yamaguchi, N., Colak-Champollion, T., Knaut, H. (2019) zGrad is a nanobody-based degron system that inactivates proteins in zebrafish. eLIFE. 8:
Schneider, J.A., Craven, T.W., Kasper, A.C., Yun, C., Haugbro, M., Briggs, E.M., Svetlov, V., Nudler, E., Knaut, H., Bonneau, R., Garabedian, M.J., Kirshenbaum, K., Logan, S.K. (2018) Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer. Nature communications. 9:4396
Wang, J., Yin, Y., Lau, S., Sankaran, J., Rothenberg, E., Wohland, T., Meier-Schellersheim, M., Knaut, H. (2018) Anosmin1 Shuttles Fgf to Facilitate Its Diffusion, Increase Its Local Concentration, and Induce Sensory Organs. Developmental Cell. 46(6):751-766.e12
Kozlovskaja-Gumbrienė, A., Yi, R., Alexander, R., Aman, A., Jiskra, R., Nagelberg, D., Knaut, H., McClain, M., Piotrowski, T. (2017) Proliferation-independent regulation of organ size by Fgf/Notch signaling. eLIFE. 6
Fuentes, F., Reynolds, E., Lewellis, S.W., Venkiteswaran, G., Knaut, H. (2016) A Plasmid Set for Efficient Bacterial Artificial Chromosome (BAC) Transgenesis in Zebrafish. G3 (Bethesda). 6(4):829-34
Nagelberg, D., Wang, J., Su, R., Torres-Vazquez, J., Targoff, K.L., Poss, K.D., Knaut, H. (2015) Origin, specification and plasticity of the great vessels of the heart.. Current biology : CB. 25:2099-2110
Venkiteswaran, G., Lewellis, S.W., Wang, J., Reynolds, E., Nicholson, C., and Knaut, H. (2013) Generation and Dynamics of an Endogenous, Self-Generated Signaling Gradient across a Migrating Tissue. Cell. 155(3):674-687
Balciuniene, J., Nagelberg, D., Walsh, K., Camerota, D., Georlette, D., Biemar, F., Bellipanni, G., and Balciunas, D. (2013) Efficient disruption of Zebrafish genes using a Gal4-containing gene trap. BMC Genomics. 14(1):619
Lewellis, S.W., Nagelberg, D., Subedi, A., Staton, A., Leblanc, M., Giraldez, A., and Knaut, H. (2013) Precise SDF1-mediated cell guidance is achieved through ligand clearance and microRNA-mediated decay. The Journal of cell biology. 200(3):337-355
Lewellis, S.W. (2013) Mechanisms of Guidance Cue Regulation During Single and Collective Cell Migration. Ph.D. Thesis. :310
Staton, A.A., Knaut, H., and Giraldez, A.J. (2011) miRNA regulation of Sdf1 chemokine signaling provides genetic robustness to germ cell migration. Nature Genetics. 43(3):204-211
Knaut, H., and Schier, A.F. (2008) Clearing the path for germ cells. Cell. 132(3):337-339
Miyasaka, N., Knaut, H., and Yoshihara, Y. (2007) Cxcl12/Cxcr4 chemokine signaling is required for placode assembly and sensory axon pathfinding in the zebrafish olfactory system. Development (Cambridge, England). 134(13):2459-2468
Knaut, H., Blader, P., Strähle, U., and Schier, A.F. (2005) Assembly of trigeminal sensory Ganglia by chemokine signaling. Neuron. 47(5):653-666
Gilmour, D., Knaut, H., Maischein, H.M., and Nüsslein-Volhard, C. (2004) Towing of sensory axons by their migrating target cells in vivo. Nature Neuroscience. 7(5):491-492
Knaut, H., Werz, C., Geisler, R., The Tübingen 2000 Screen Consortium, Nüsslein-Volhard, C. (2003) A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor. Nature. 421(6920):279-282
Ciruna, B., Weidinger, G., Knaut, H., Thisse, B., Thisse, C., Raz, E., and Schier, A.F. (2002) Production of maternal-zygotic mutant zebrafish by germ-line replacement. Proceedings of the National Academy of Sciences of the United States of America. 99(23):14919-14924
Knaut, H., Steinbeisser, H., Schwarz, H., and Nüsslein-Volhard, C. (2002) An evolutionary conserved region in the vasa 3'UTR targets RNA translation to the germ cells in the zebrafish. Current biology : CB. 12(6):454-466
Knaut, H., Pelegri, F., Bohmann, K., Schwarz, H., and Nüsslein-Volhard, C. (2000) Zebrafish vasa RNA but not its protein is a component of the germ plasm and segregates asymmetrically before germline specification. The Journal of cell biology. 149(4):875-888
Pelegri, F., Knaut, H., Maischein, H.M., Schulte-Merker, S., and Nüsslein-Volhard, C. (1999) A mutation in the zebrafish maternal-effect gene nebel affects furrow formation and vasa RNA localization. Current biology : CB. 9(24):1431-1440
Geisler, R., Rauch, G.J., Baier, H., van Bebber, F., Brobeta, L., Dekens, M.P., Finger, K., Fricke, C., Gates, M.A., Geiger, H., Geiger-Rudolph, S., Gilmour, D., Glaser, S., Gnugge, L., Habeck, H., Hingst, K., Holley, S., Keenan, J., Kirn, A., Knaut, H., Lashkari, D., Maderspacher, F., Martyn, U., Neuhauss, S., Neumann, C., Nicolson, T., Pelegri, F., Ray, R., Rick, J.M., Roehl, H., Roeser, T., Schauerte, H.E., Schier, A.F., Schönberger, U., Schönthaler, H.-B., Schulte-Merker, S., Seydler, C., Talbot, W.S., Weiler, C., Nüsslein-Volhard, C., and Haffter, P. (1999) A radiation hybrid map of the zebrafish genome. Nature Genetics. 23(1):86-89