ZFIN Lab: Vastenhouw Lab

ZFIN ID: ZDB-LAB-120601-1

Vastenhouw Lab

PI/Director:	Vastenhouw, Nadine
Contact Person:	Vastenhouw, Nadine
Email:	vastenhouw@mpi-cbg.de
URL:	http://www.mpi-cbg.de/research/research-groups/nadine-vastenhouw.html
Address:	Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) Pfotenhauerstrasse 108 01307 Dresden Germany
Country:	Germany
Phone:	+49 (0)351 210 2411
Fax:	+49 (0)351 210 1600
Line Designation:	None assigned

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Oda, H., Sato, Y., Kawashima, S.A., Fujiwara, Y., Pálfy, M., Wu, E., Vastenhouw, N.L., Kanai, M., Kimura, H. (2023) Actin filaments accumulated in the nucleus and remain in the vicinity of condensing chromosomes during prophase in zebrafish early embryo. Biology Open. 12(5):

Kuznetsova, K., Chabot, N.M., Ugolini, M., Wu, E., Lalit, M., Oda, H., Sato, Y., Kimura, H., Jug, F., Vastenhouw, N.L. (2022) Nanog organizes transcription bodies. Current biology : CB. 33(1):164-173.e5

Hilbert, L., Sato, Y., Kuznetsova, K., Bianucci, T., Kimura, H., Jülicher, F., Honigmann, A., Zaburdaev, V., Vastenhouw, N.L. (2021) Transcription organizes euchromatin via microphase separation. Nature communications. 12:1360

Abrams, E.W., Fuentes, R., Marlow, F.L., Kobayashi, M., Zhang, H., Lu, S., Kapp, L., Joseph, S.R., Kugath, A., Gupta, T., Lemon, V., Runke, G., Amodeo, A.A., Vastenhouw, N.L., Mullins, M.C. (2020) Molecular genetics of maternally-controlled cell divisions. PLoS Genetics. 16:e1008652

Pálfy, M., Schulze, G., Valen, E., Vastenhouw, N.L. (2020) Chromatin accessibility established by Pou5f3, Sox19b and Nanog primes genes for activity during zebrafish genome activation. PLoS Genetics. 16:e1008546

Sato, Y., Hilbert, L., Oda, H., Wan, Y., Heddleston, J.M., Chew, T.L., Zaburdaev, V., Keller, P., Lionnet, T., Vastenhouw, N., Kimura, H. (2019) Histone H3K27 acetylation precedes active transcription during zebrafish zygotic genome activation as revealed by live-cell analysis. Development (Cambridge, England). 146(19):

Vopalensky, P., Pralow, S., Vastenhouw, N.L. (2018) Reduced expression of the Nodal coreceptor Oep causes loss of mesendodermal competence in zebrafish. Development (Cambridge, England). 145(5)

Stapel, L.C., Broaddus, C., Vastenhouw, N.L. (2018) Detection and Automated Analysis of Single Transcripts at Subcellular Resolution in Zebrafish Embryos. Methods in molecular biology (Clifton, N.J.). 1649:143-162

Kumar, M., Joseph, S.R., Augsburg, M., Bogdanova, A., Drechsel, D., Vastenhouw, N.L., Buchholz, F., Gentzel, M., Shevchenko, A. (2017) MS Western, a method of multiplexed absolute protein quantification is a practical alternative to Western blotting. Molecular & cellular proteomics : MCP. 17(2):384-396

Stapel, L.C., Zechner, C., Vastenhouw, N.L. (2017) Uniform gene expression in embryos is achieved by temporal averaging of transcription noise. Genes & Development. 31(16):1635-1640

Boothe, T., Hilbert, L., Heide, M., Berninger, L., Huttner, W.B., Zaburdaev, V., Vastenhouw, N.L., Myers, E.W., Drechsel, D.N., Rink, J.C. (2017) A tunable refractive index matching medium for live imaging cells, tissues and model organisms. eLIFE. 6

Joseph, S.R., Pálfy, M., Hilbert, L., Kumar, M., Karschau, J., Zaburdaev, V., Shevchenko, A., Vastenhouw, N.L. (2017) Competition between histone and transcription factor binding regulates the onset of transcription in zebrafish embryos. eLIFE. 6

Stapel, L.C., Lombardot, B., Broaddus, C., Kainmueller, D., Jug, F., Myers, E.W., Vastenhouw, N.L. (2016) Automated detection and quantification of single RNAs at cellular resolution in zebrafish embryos. Development (Cambridge, England). 143(3):540-6

Stapel, L.C., and Vastenhouw, N.L. (2014) Message control in developmental transitions; deciphering chromatin's role using zebrafish genomics. Briefings in Functional Genomics. 13(2):106-20

Zhang, Y., Vastenhouw, N.L., Feng, J., Fu, K., Wang, C., Ge, Y., Pauli, A., van Hummelen, P., Schier, A.F., and Liu, X.S. (2014) Canonical nucleosome organization at promoters forms during genome activation. Genome research. 24(2):260-6

Vastenhouw, N.L., and Schier, A.F. (2012) Bivalent histone modifications in early embryogenesis. Current opinion in cell biology. 24(3):374-386

Pauli, A., Valen, E., Lin, M.F., Garber, M., Vastenhouw, N.L., Levin, J.Z., Fan, L., Sandelin, A., Rinn, J.L., Regev, A., and Schier, A.F. (2012) Systematic identification of long non-coding RNAs expressed during zebrafish embryogenesis. Genome research. 22(3):577-591

Vastenhouw, N.L., Zhang, Y., Woods, I.G., Imam, F., Regev, A., Liu, X.S., Rinn, J., and Schier, A.F. (2010) Chromatin signature of embryonic pluripotency is established during genome activation. Nature. 464(7290):922-926