ZFIN Lab: Krause Lab

ZFIN ID: ZDB-LAB-110418-1

Krause Lab

PI/Director:	Krause, Henry
Contact Person:	Krause, Henry
Email:	h.krause@utoronto.ca
URL:	http://www.utoronto.ca/krause/
Address:	160 College Street, room 504 Donelly Centre for Cellular and Biomolecular Research University of Toronto, Toronto, M5S 3E1 Ontario CANADA
Country:	Canada
Phone:	416-978-5531
Fax:	416-978-8528
Line Designation:	None assigned

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Nelson, Meryl Post-Doc	Tiefenbach, Jens Post-Doc	Shih, Norrapat Graduate Student
Cheng, Victor Technical Staff	Hu, Chun Technical Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Sahin, C., Magomedova, L., Ferreira, T.A.M., Liu, J., Tiefenbach, J., Alves, P.S., Queiroz, F.J.G., Oliveira, A.S., Bhattacharyya, M., Grouleff, J., Nogueira, P.C.N., Silveira, E.R., Moreira, D.C., Leite, J.R.S.A., Brand, G.D., Uehling, D., Poda, G., Krause, H., Cummins, C.L., Romeiro, L.A.S. (2022) Phenolic Lipids Derived from Cashew Nut Shell Liquid to Treat Metabolic Diseases. Journal of medicinal chemistry. 65(3):1961-1978

Burgess, J., Burrows, J.T., Sadhak, R., Chiang, S., Weiss, A., D'Amata, C., Molinaro, A.M., Zhu, S., Long, M., Hu, C., Krause, H.M., Pearson, B.J. (2020) An optimized QF-binary expression system for use in zebrafish. Developmental Biology. 465(2):144-156

Reunov, A., Yakovlev, K., Hu, J., Reunova, Y., Komkova, A., Alexandrova, Y., Pimenova, E., Tiefenbach, J., Krause, H. (2019) Close association between vasa-positive germ plasm granules and mitochondria correlates with cytoplasmic localization of 12S and 16S mtrRNAs during zebrafish spermatogenesis. Differentiation; research in biological diversity. 109:34-41

Evans, R.J., Pline, K., Loynes, C.A., Needs, S., Aldrovandi, M., Tiefenbach, J., Bielska, E., Rubino, R.E., Nicol, C.J., May, R.C., Krause, H.M., O'Donnell, V.B., Renshaw, S.A., Johnston, S.A. (2019) 15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection. PLoS pathogens. 15:e1007597

Magomedova, L., Tiefenbach, J., Zilberman, E., Le Billan, F., Voisin, V., Saikali, M., Boivin, V., Robitaille, M., Gueroussov, S., Irimia, M., Ray, D., Patel, R., Xu, C., Jeyasuria, P., Bader, G.D., Hughes, T.R., Morris, Q.D., Scott, M.S., Krause, H., Angers, S., Blencowe, B.J., Cummins, C.L. (2019) ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development. Nucleic acids research. 47(6):2856-2870

Tiefenbach, J., Magomedova, L., Liu, J., Reunov, A.A., Tsai, R., Eappen, N.S., Jockusch, R.A., Nislow, C., Cummins, C.L., Krause, H.M. (2018) Idebenone and coenzyme Q₁₀ are novel PPARα/γ ligands, with potential for treatment of fatty liver diseases.. Disease models & mechanisms. 11(9):

Zhang, D.L., Hu, C.X., Li, D.H., and Liu, Y.D. (2013) Zebrafish locomotor capacity and brain acetylcholinesterase activity is altered by Aphanizomenon flos-aquae DC-1 aphantoxins. Aquatic toxicology (Amsterdam, Netherlands). 138-139:139-149

Delvecchio, C., Tiefenbach, J., and Krause, H.M. (2011) The Zebrafish: A Powerful Platform for In Vivo, HTS Drug Discovery. Assay and drug development technologies. 9(4):354-61

Tiefenbach, J., Moll, P.R., Nelson, M.R., Hu, C., Baev, L., Kislinger, T., and Krause, H.M. (2010) A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery. PLoS One. 5(3):e9797