ZFIN ID: ZDB-LAB-110119-1
Alsina Lab
PI/Director: Alsina, Berta
Contact Person: Sas, Miquel
Email: miquel.sas@upf.edu
URL: http://www.upf.edu/devbiol/projectes/Alsina_lab.html
Address: Laboratory of Developmental Biology Universitat Pompeu Fabra-PRBB Dr. Aiguader 88, 08003 Barcelona, Spain
Country: Spain
Phone: +34 933160817
Line Designation: pfu


Neurogenesis and patterning mechanisms in the inner ear, sensory gene cis- regulatory elements.

Moreno, Alex Robert Post-Doc Radosevic, Marija Graduate Student Linares, Marta Technical Staff
Sas, Miquel Technical Staff

Taberner, L., Bañón, A., Alsina, B. (2020) Sensory Neuroblast Quiescence Depends on Vascular Cytoneme Contacts and Sensory Neuronal Differentiation Requires Initiation of Blood Flow. Cell Reports. 32:107903
Taberner, L., Bañón, A., Alsina, B. (2017) Anatomical map of the cranial vasculature and sensory ganglia. Journal of anatomy. 232(3):431-439
Hoijman, E., Fargas, L., Blader, P., Alsina, B. (2017) Pioneer neurog1 expressing cells ingress into the otic epithelium and instruct neuronal specification.. eLIFE. 6
Alsina, B., Whitfield, T.T. (2017) Sculpting the labyrinth: morphogenesis of the developing inner ear. Seminars in cell & developmental biology. 65:47-59
Rubbini, D., Robert-Moreno, À., Hoijman, E., Alsina, B. (2015) Retinoic Acid Signaling Mediates Hair Cell Regeneration by Repressing p27kip and sox2 in Supporting Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35:15752-66
Hoijman, E., Rubbini, D., Colombelli, J., Alsina, B. (2015) Mitotic cell rounding and epithelial thinning regulate lumen growth and shape. Nature communications. 6:7355
Iturbide, A., Pascual-Reguant, L., Fargas, L., Cebrià, J.P., Alsina, B., García de Herreros, A., Peiró, S. (2015) LOXL2 Oxidizes Methylated TAF10 and Controls TFIID-Dependent Genes during Neural Progenitor Differentiation. Molecular Cell. 58(5):755-66
Radosevic, M., Fargas, L., Alsina, B. (2014) The Role of her4 in Inner Ear Development and Its Relationship with Proneural Genes and Notch Signalling. PLoS One. 9:e109860
Mora, N., Almudi, I., Alsina, B., Corominas, M., and Serras, F. (2013) The Beta-amyloid protein precursor like (Appl) is a Ras1/MAPK regulated gene required for axonal targeting in Drosophila photoreceptor neurons. The Journal of cell biology. 126(1):53-59
Radosevic, M., Robert-Moreno, A., Coolen, M., Bally-Cuif, L., and Alsina, B. (2011) Her9 represses neurogenic fate downstream of Tbx1 and retinoic acid signaling in the inner ear. Development (Cambridge, England). 138(3):397-408
Robert-Moreno, A., Naranjo, S., de la Calle-Mustienes, E., Gomez-Skarmeta, J.L., and Alsina, B. (2010) Characterization of new otic enhancers of the pou3f4 gene reveal distinct signaling pathway regulation and spatio-temporal patterns. PLoS One. 5(12):e15907
Naranjo, S., Voesenek, K., de la Calle-Mustienes, E., Robert-Moreno, A., Kokotas, H., Grigoriadou, M., Economides, J., Van Camp, G., Hilgert, N., Moreno, F., Alsina, B., Petersen, M.B., Kremer, H., and Gómez-Skarmeta, J.L. (2010) Multiple enhancers located in a 1-Mb region upstream of POU3F4 promote expression during inner ear development and may be required for hearing. Human genetics. 128(4):411-419
Abello, G., and Alsina, B. (2007) Establishment of a proneural field in the inner ear. The International journal of developmental biology. 51(6-7):483-493
Aragon, F., Vazquez-Echeverria, C., Ulloa, E., Reber, M., Cereghini, S., Alsina, B., Giraldez, F., and Pujades, C. (2005) vHnf1 regulates specification of caudal rhombomere identity in the chick hindbrain. Developmental dynamics : an official publication of the American Association of Anatomists. 234(3):567-576