ZFIN Lab: Andrew Perkins Lab

ZFIN ID: ZDB-LAB-080606-1

Andrew Perkins Lab

PI/Director:	Perkins, Andrew
Contact Person:	Lawton, Angela
URL:
Address:	Institute for Molecular Bioscience University of Queensland Carmody Rd Queensland Brisbane, 4072 Australia
Country:	Australia
Phone:
Fax:
Line Designation:	None assigned

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Wilkins, Simon Graduate Student

Griffin, Aliesha Research Staff

Lawton, Angela Fish Facility Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Griffin, A., Anvar, M., Hamling, K., Baraban, S.C. (2020) Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model. Frontiers in pharmacology. 11:464

Oakes, J.A., Li, N., Wistow, B.R.C., Griffin, A., Barnard, L., Storbeck, K.H., Cunliffe, V.T., Krone, N.P. (2019) Ferredoxin 1b deficiency leads to testis disorganization, impaired spermatogenesis and feminization in zebrafish. Endocrinology. 160(10):2401-2416

Griffin, A.L., Jaishankar, P., Grandjean, J.M., Olson, S.H., Renslo, A.R., Baraban, S.C. (2019) Zebrafish studies identify serotonin receptors mediating antiepileptic activity in Dravet syndrome. Brain communications. 1:fcz008

Griffin, A., Hamling, K.R., Hong, S., Anvar, M., Lee, L.P., Baraban, S.C. (2018) Preclinical Animal Models for Dravet Syndrome: Seizure Phenotypes, Comorbidities and Drug Screening. Frontiers in pharmacology. 9:573

Lu, H., Galeano, M.C.R., Ott, E., Kaeslin, G., Kausalya, P.J., Kramer, C., Ortiz-Brüchle, N., Hilger, N., Metzis, V., Hiersche, M., Tay, S.Y., Tunningley, R., Vij, S., Courtney, A.D., Whittle, B., Wühl, E., Vester, U., Hartleben, B., Neuber, S., Frank, V., Little, M.H., Epting, D., Papathanasiou, P., Perkins, A.C., Wright, G.D., Hunziker, W., Gee, H.Y., Otto, E.A., Zerres, K., Hildebrandt, F., Roy, S., Wicking, C., Bergmann, C. (2017) Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease. Nature Genetics. 49:1025–1034

Griffin, A., Hamling, K.R., Knupp, K., Hong, S., Lee, L.P., Baraban, S.C. (2017) Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome. Brain : a journal of neurology. 140(3):669-683

Zhang, R., Knapp, M., Suzuki, K., Kajioka, D., Schmidt, J.M., Winkler, J., Yilmaz, Ö., Pleschka, M., Cao, J., Kockum, C.C., Barker, G., Holmdahl, G., Beaman, G., Keene, D., Woolf, A.S., Cervellione, R.M., Cheng, W., Wilkins, S., Gearhart, J.P., Sirchia, F., Di Grazia, M., Ebert, A.K., Rösch, W., Ellinger, J., Jenetzky, E., Zwink, N., Feitz, W.F., Marcelis, C., Schumacher, J., Martinón-Torres, F., Hibberd, M.L., Khor, C.C., Heilmann-Heimbach, S., Barth, S., Boyadjiev, S.A., Brusco, A., Ludwig, M., Newman, W., Nordenskjöld, A., Yamada, G., Odermatt, B., Reutter, H. (2017) ISL1 is a major susceptibility gene for classic bladder exstrophy and a regulator of urinary tract development. Scientific Reports. 7:42170

Griffin, A., Parajes, S., Weger, M., Zaucker, A., Taylor, A.E., O'Neil, D.M., Müller, F., Krone, N. (2016) Ferredoxin 1b (Fdx1b) is the essential mitochondrial redox partner for cortisol biosynthesis in zebrafish. Endocrinology. 157(3):1122-34

Jülich, D., Cobb, G., Melo, A.M., McMillen, P., Lawton, A.K., Mochrie, S.G., Rhoades, E., Holley, S.A. (2015) Cross-Scale Integrin Regulation Organizes ECM and Tissue Topology. Developmental Cell. 34(1):33-44

Markmiller, S., Cloonan, N., Lardelli, R.M., Doggett, K., Keightley, M.C., Boglev, Y., Trotter, A.J., Ng, A.Y., Wilkins, S.J., Verkade, H., Ober, E.A., Field, H.A., Grimmond, S.M., Lieschke, G.J., Stainier, D.Y., and Heath, J.K. (2014) Minor class splicing shapes the zebrafish transcriptome during development. Proceedings of the National Academy of Sciences of the United States of America. 111(8):3062-3067

Parajes, S., Griffin, A., Taylor, A.E., Rose, I.T., Miguel-Escalada, I., Hadzhiev, Y., Arlt, W., Shackleton, C., Muller, F., and Krone, N. (2013) Redefining the initiation and maintenance of zebrafish interrenal steroidogenesis by characterizing the key enzyme Cyp11a2. Endocrinology. 154(8):2702-11

Kovacevic, I., Hu, J., Siehoff-Icking, A., Opitz, N., Griffin, A., Perkins, A.C., Munn, A.L., Müller-Esterl, W., Popp, R., Fleming, I., Jungblut, B., Hoffmeister, M., and Oess, S. (2012) The F-BAR protein NOSTRIN participates in FGF signal transduction and vascular development. The EMBO journal. 31(15):3309-3322

Castranova, D., Lawton, A., Lawrence, C., Baumann, D.P., Best, J., Coscolla, J., Doherty, A., Ramos, J., Hakkesteeg, J., Wang, C., Wilson, C., Malley, J., and Weinstein, B.M. (2011) The Effect of Stocking Densities on Reproductive Performance in Laboratory Zebrafish (Danio rerio). Zebrafish. 8(3):141-6

Amaral, P.P., Neyt, C., Wilkins, S.J., Askarian-Amiri, M.E., Sunkin, S.M., Perkins, A.C., and Mattick, J.S. (2009) Complex architecture and regulated expression of the Sox2ot locus during vertebrate development. RNA (New York, N.Y.). 15(11):2013-2027

Kassahn, K.S., Dang, V.T., Wilkins, S.J., Perkins, A.C., and Ragan, M.A. (2009) Evolution of gene function and regulatory control after whole-genome duplication: Comparative analyses in vertebrates. Genome research. 19(8):1404-1418

Wilkins, S.J. (2009) Global analysis of transcriptional control driving Zebrafish gastrulation. Ph.D. Thesis.

Wilkins, S.J., Yoong, S., Verkade, H., Mizoguchi, T., Plowman, S.J., Hancock, J.F., Kikuchi, Y., Heath, J.K., and Perkins, A.C. (2008) Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation. Developmental Biology. 314(1):12-22

Gardiner, M.R., Gongora, M.M., Grimmond, S.M., and Perkins, A.C. (2007) A global role for zebrafish klf4 in embryonic erythropoiesis. Mechanisms of Development. 124(9-10):762-774

Kinna, G., Kolle, G., Carter, A., Key, B., Lieschke, G.J., Perkins, A., and Little, M.H. (2006) Knockdown of zebrafish crim1 results in a bent tail phenotype with defects in somite and vascular development. Mechanisms of Development. 123(4):277-287

Gardiner, M.R., Daggett, D.F., Zon, L.I., and Perkins, A.C. (2005) Zebrafish KLF4 is essential for anterior mesendoderm/pre-polster differentiation and hatching. Developmental Dynamics : an official publication of the American Association of Anatomists. 234(4):992-996