ZFIN ID: ZDB-LAB-080214-1
Russell Lab
PI/Director: Russell, Claire
Contact Person: Russell, Claire
Email: crussell@rvc.ac.uk
URL: http://www.rvc.ac.uk/AboutUs/Staff/crussell/
Address: Royal Veterinary College Department of Veterinary Basic Sciences Royal College Street London NW10TU UK
Country: United Kingdom
Phone: +44 (0) 2074681179
Fax: +44 (0) 2073882342
Line Designation: None assigned


GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available


STATEMENT OF RESEARCH INTERESTS
Current Research Interests:
Left-right lateralisation of the brain
Zebrafish models of Neuronal Ceroid Lipofuscinosis
Retinal development and coloboma

Former Research Interests:
Zebrafish nervous system development
Drosophila axon guidance
Drosophila imaginal disc development

Biography:
BSc HONS in Biochemistry, Imperial College, London, UK
DPhil in Genes and Development, University of Sussex, Falmer, UK
Postdoctoral Researcher , Imperial College, London, UK
Postdoctoral Researcher, King's College, London, UK
Postdoctoral Researcher, UCL, London, UK
Senior Postdoctoral Researcher, UCL, London, UK
Lecturer in Veterinary Basic Sciences, Royal Veterinary College, London, UK


LAB MEMBERS


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Huber, R.J., Hughes, S.M., Liu, W., Morgan, A., Tuxworth, R.I., Russell, C. (2019) The contribution of multicellular model organisms to neuronal ceroid lipofuscinosis research. Biochimica et biophysica acta. Molecular basis of disease. 1866(9):165614
Martín-Jiménez, R., Faccenda, D., Allen, E., Reichel, H.B., Arcos, L., Ferraina, C., Strobbe, D., Russell, C., Campanella, M. (2018) Reduction of the ATPase inhibitory factor 1 (IF1) leads to visual impairment in vertebrates.. Cell Death & Disease. 9:669
Outtandy, P., Russell, C., Kleta, R., Bockenhauer, D. (2018) Zebrafish as a model for kidney function and disease. Pediatric nephrology (Berlin, Germany). 34(5):751-762
Wager, K., Zdebik, A.A., Fu, S., Cooper, J.D., Harvey, R.J., Russell, C. (2016) Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease). PLoS One. 11:e0157365
Solchenberger, B., Russell, C., Kremmer, E., Haass, C., Schmid, B. (2015) Granulin Knock Out Zebrafish Lack Frontotemporal Lobar Degeneration and Neuronal Ceroid Lipofuscinosis Pathology. PLoS One. 10:e0118956
Cunliffe, V.T., Baines, R.A., Giachello, C.N., Lin, W.H., Morgan, A., Reuber, M., Russell, C., Walker, M.C., Williams, R.S. (2015) Epilepsy research methods update: Understanding the causes of epileptic seizures and identifying new treatments using non-mammalian model organisms. Seizure. 24C:44-51
Ivanes, F., Faccenda, D., Gatliff, J., Ahmed, A.A., Cocco, S., Cheng, C.H., Allan, E., Russell, C., Duchen, M.R., Campanella, M. (2014) The compound BTB06584 is an IF1 -dependent selective inhibitor of the mitochondrial F1 Fo-ATPase. British journal of pharmacology. 171(18):4193-206
Wager, K., Mahmood, F., Russell, C. (2014) Modelling inborn errors of metabolism in zebrafish. Journal of inherited metabolic disease. 37(4):483-95
Zdebik, A.A., Mahmood, F., Stanescu, H.C., Kleta, R., Bockenhauer, D., and Russell, C. (2013) Epilepsy in kcnj10 Morphant Zebrafish Assessed with a Novel Method for Long-Term EEG Recordings. PLoS One. 8(11):e79765
Wager, K., and Russell, C. (2013) Mitophagy and neurodegeneration: The zebrafish model system. Autophagy. 9(11):1693-1709
Mahmood, F., Fu, S., Cooke, J., Wilson, S.W., Cooper, J.D., and Russell, C. (2013) A zebrafish model of CLN2 disease is deficient in tripeptidyl peptidase 1 and displays progressive neurodegeneration accompanied by a reduction in proliferation. Brain : a journal of neurology. 136(Pt 5):1488-507
Mahmood, F., Mozere, M., Zdebik, A.A., Stanescu, H.C., Tobin, J., Beales, P.L., Kleta, R., Bockenhauer, D., and Russell, C. (2013) Generation and validation of a zebrafish model of EAST (Epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome. Disease models & mechanisms. 6(3):652-60
Brennan, C., Dosch, R., Haramis, A.P., Luckenbacher, T., Martinez-Morales, J.R., Moro, E., Polok, B., Ramesh, T.M., Russell, C., Argenton, F., and Strähle, U. (2010) Report of the European Zebrafish Principal Investigator Meeting in Padua, Italy, March 18-22, 2010. Zebrafish. 7(3):305-310
Regan, J.C., Concha, M.L., Roussigne, M., Russell, C., and Wilson, S.W. (2009) An Fgf8-dependent bistable cell migratory event establishes CNS asymmetry. Neuron. 61(1):27-34
Bianco, I.H., Carl, M., Russell, C., Clarke, J.D., and Wilson, S.W. (2008) Brain asymmetry is encoded at the level of axon terminal morphology. Neural Development. 3:9
Cooper, J.D., Russell, C., and Mitchison, H.M. (2006) Progress towards understanding disease mechanisms in small vertebrate models of neuronal ceroid lipofuscinosis. Biochimica et biophysica acta. Molecular basis of disease. 1762(10):873-889
Aizawa, H., Bianco, I.H., Hamaoka, T., Miyashita, T., Uemura, O., Concha, M.L., Russell, C., Wilson, S.W., and Okamoto, H. (2005) Laterotopic Representation of Left-Right Information onto the Dorso-Ventral Axis of a Zebrafish Midbrain Target Nucleus. Current biology : CB. 15(3):238-243
Norton, W.H., Mangoli, M., Lele, Z., Pogoda, H.M., Diamond, B., Mercurio, S., Russell, C., Teraoka, H., Stickney, H.L., Rauch, G.J., Heisenberg, C.P., Houart, C., Schilling, T.F., Frohnhoefer, H.G., Rastegar, S., Neumann, C.J., Gardiner, R.M., Strähle, U., Geisler, R., Rees, M., Talbot, W.S., and Wilson, S.W. (2005) Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones. Development (Cambridge, England). 132(4):645-658
Teraoka, H., Russell, C., Regan, J., Chandrasekhar, A., Concha, M.L., Yokoyama, R., Higashi, K., Take-Uchi, M., Dong, W., Hiraga, T., Holder, N., and Wilson, S.W. (2004) Hedgehog and Fgf signaling pathways regulate the development of tphR-expressing serotonergic raphe neurons in zebrafish embryos. Journal of neurobiology. 60(3):275-288
Paukert, M., Sidi, S., Russell, C., Siba, M., Wilson, S.W., Nicolson, T., and Grunder, S. (2004) A family of acid-sensing ion channels (ASICs) from the zebrafish: Widespread expression in the central nervous system suggests a conserved role in neuronal communication. The Journal of biological chemistry. 279(18):18783-18791
Concha, M.L., Russell, C., Regan, J.C., Tawk, M., Sidi, S., Gilmour, D.T., Kapsimali, M., Sumoy, L., Goldstone, K., Amaya, E., Kimelman, D., Nicolson, T., Gründer, S., Gomperts, M., Clarke, J.D.W., and Wilson, S.W. (2003) Local tissue interactions across the dorsal midline of the forebrain establish CNS laterality. Neuron. 39(3):423-438
Russell, C. (2003) The roles of Hedgehogs and Fibroblast Growth Factors in eye development and retinal cell rescue. Vision Research. 43(8):899-912
Concha, M.L., Burdine, R.D., Russell, C., Schier, A.F., and Wilson, S.W. (2000) A nodal signaling pathway regulates the laterality of neuroanatomical asymmetries in the zebrafish forebrain. Neuron. 28(2):399-409
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