ZFIN Lab: Litman Lab

ZFIN ID: ZDB-LAB-010308-4

Litman Lab

PI/Director:	Litman, Gary W.
Contact Person:	Litman, Gary W.
Email:	litmang@allkids.org
URL:
Address:	Children's Research Institute - 3008 University of South Florida 140 Seventh Avenue South St. Petersburg, FL 33701 USA
Country:	United States
Phone:	(727) 553-3601
Fax:	(727) 553-3610
Line Designation:	None assigned

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Mueller, Gail Research Staff

Scapora, Diana Research Staff

Haire, Robert

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Wcisel, D.J., Dornburg, A., McConnell, S.C., Hernandez, K.M., Andrade, J., de Jong, J.L.O., Litman, G.W., Yoder, J.A. (2022) A highly diverse set of novel immunoglobulin-like transcript (NILT) genes in zebrafish indicates a wide range of functions with complex relationships to mammalian receptors. Immunogenetics. 75(1):53-69

Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37

Rodriguez-Nunez, I., Wcisel, D.J., Litman, R.T., Litman, G.W., Yoder, J.A. (2016) The identification of additional zebrafish DICP genes reveals haplotype variation and linkage to MHC class I genes. Immunogenetics. 68(4):295-312

Rodríguez-Nunez, I., Wcisel, D.J., Litman, G.W., and Yoder, J.A. (2014) Multigene families of immunoglobulin domain-containing innate immune receptors in zebrafish: Deciphering the differences. Developmental and comparative immunology. 46(1):24-34

Kortum, A.N., Rodriguez-Nunez, I., Yang, J., Shim, J., Runft, D., O'Driscoll, M.L., Haire, R.N., Cannon, J.P., Turner, P.M., Litman, R.T., Kim, C.H., Neely, M.N., Litman, G.W., and Yoder, J.A. (2014) Differential expression and ligand binding indicate alternative functions for zebrafish polymeric immunoglobulin receptor (pIgR) and a family of pIgR-like (PIGRL) proteins. Immunogenetics. 66(4):267-279

Amemiya, C.T., Alfoldi, J., Lee, A.P., Fan, S., Philippe, H., MacCallum, I., Braasch, I., Manousaki, T., Schneider, I., Rohner, N., Organ, C., Chalopin, D., Smith, J.J., Robinson, M., Dorrington, R.A., Gerdol, M., Aken, B., Biscotti, M.A., Barucca, M., Baurain, D., Berlin, A.M., Blatch, G.L., Buonocore, F., Burmester, T., Campbell, M.S., Canapa, A., Cannon, J.P., Christoffels, A., de Moro, G., Edkins, A.L., Fan, L., Fausto, A.M., Feiner, N., Forconi, M., Gamieldien, J., Gnerre, S., Gnirke, A., Goldstone, J.V., Haerty, W., Hahn, M.E., Hesse, U., Hoffmann, S., Johnson, J., Karchner, S.I., Karaku, S., Lara, M., Levin, J.Z., Litman, G.W., Mauceli, E., Miyake, T., Mueller, M.G., Nelson, D.R., Nitsche, A., Olmo, E., Ota, T., Pallavicini, A., Panji, S., Picone, B., Ponting, C.P., Prohaska, S.J., Przybylski, D., Saha, N.R., Ravi, V., Ribeiro, F.J., Sauka-Spengler, T., Scapigliati, G., Searle, S.M.J., Sharpe, T., Simakov, O., Stadler, P.F., Stegeman, J.J., Sumiyama, K., Tabbaa, D., Tafer, H., Turner-Maier, J., van Heusden, P., White, S., Williams, L., Yandell, M., Brinkmann, H., Volff, J.N., Tabin, C.J., Shubin, N., Schartl, M., Jaffe, D.B., Postlethwait, J.H., Venkatesh, B., Palma, F.D., Lander, E.S., Meyer, A., and Lindblad-Toh, K. (2013) The African coelacanth genome provides insights into tetrapod evolution. Nature. 496:311-316

Haire, R.N., Cannon, J.P., O'Driscoll, M.L., Ostrov, D.A., Mueller, M.G., Turner, P.M., Litman, R.T., Litman, G.W., and Yoder, J.A. (2012) Genomic and functional characterization of the diverse immunoglobulin domain-containing protein (DICP) family. Genomics. 99(5):282-291

Shah, R.N., Rodriguez-Nunez, I., Eason, D.D., Haire, R.N., Bertrand, J.Y., Wittamer, V., Traver, D., Nordone, S.K., Litman, G.W., and Yoder, J.A. (2012) Development and characterization of anti-nitr9 antibodies. Advances in hematology. 2012:596925

Yoder, J.A., and Litman, G.W. (2011) The phylogenetic origins of natural killer receptors and recognition: relationships, possibilities, and realities. Immunogenetics. 63(3):123-141

Yoder, J.A., Turner, P.M., Wright, P.D., Wittamer, V., Bertrand, J.Y., Traver, D., and Litman, G.W. (2010) Developmental and tissue-specific expression of NITRs. Immunogenetics. 62(2):117-122

Desai, S., Heffelfinger, A.K., Orcutt, T.M., Litman, G.W., and Yoder, J.A. (2008) The medaka novel immune-type receptor (NITR) gene clusters reveal an extraordinary degree of divergence in variable domains. BMC Evolutionary Biology. 8:177

Yoder, J.A., Cannon, J.P., Litman, R.T., Murphy, C., Freeman, J.L., and Litman, G.W. (2008) Evidence for a transposition event in a second NITR gene cluster in zebrafish. Immunogenetics. 60(5):257-265

Yoder, J.A., Orcutt, T.M., Traver, D., and Litman, G.W. (2007) Structural characteristics of zebrafish orthologs of adaptor molecules that associate with transmembrane immune receptors. Gene. 401(1-2):154-164

Wei, S., Zhou, J.M., Chen, X., Shah, R.N., Liu, J., Orcutt, T.M., Traver, D., Djeu, J.Y., Litman, G.W., and Yoder, J.A. (2007) The zebrafish activating immune receptor Nitr9 signals via Dap12. Immunogenetics. 59(10):813-821

Yoder, J.A., Litman, R.T., Mueller, M.G., Desai, S., Dobrinski, K.P., Montgomery, J.S., Buzzeo, M.P., Ota, T., Amemiya, C.T., Trede, N.S., Wei, S., Djeu, J.Y., Humphray, S., Jekosch, K., Hernandez Prada, J.A., Ostrov, D.A., and Litman, G.W. (2004) Resolution of the novel immune-type receptor gene cluster in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 101(44):15706-15711

Traver, D., Herbomel, P., Patton, E.E., Murphey, R.D., Yoder, J.A., Litman, G.W., Catic, A., Amemiya, C.T., Zon, L.I., and Trede, N.S. (2003) The zebrafish as a model organism to study development of the immune system. Advances in immunology. 81:253-330

Yoder, J.A., Nielsen, M.E., Amemiya, C.T., and Litman, G.W. (2002) Zebrafish as an immunological model system. Microbes and infection. 4(14):1469-1478

Yoder, J.A., Hawke, N.A., Eason, D.D., Mueller, M.G., Davids, B.J., Gillin, F.D., and Litman, G.W. (2002) BIVM, a novel gene widely distributed among Deuterostomes, shares a core sequence with an unusual gene in Giardia lamblia. Genomics. 79(6):750-755

Yoder, J.A., Mueller, M.G., Wei, S., Corliss, B.C., Prather, D.M., Willis, T., Litman, R.T., Djeu, J.Y., and Litman, G.W. (2001) Immune-type receptor genes in zebrafish share genetic and functional properties with genes encoded by the mammalian leukocyte receptor cluster. Proceedings of the National Academy of Sciences of the United States of America. 98(12):6771-6776

Litman, G.W., Hawke, N.A., and Yoder, J.A. (2001) Novel immune-type receptor genes. Immunological reviews. 181:250-259

Yoder, J.A. and Litman, G.W. (2001) Corrigendum to: "The zebrafish fth1, slc3a2, men1, pc, fgf3 and cycd1 genes define two regions of conserved synteny between linkage group 7 and human chromosome 11q13". Gene. 269(1-2):227

Yoder, J.A. and Litman, G.W. (2000) The zebrafish fth1, slc3a2, men1, pc, fgf3 and cycd1 genes define two regions of conserved synteny between linkage group 7 and human chromosome 11q13. Gene. 261:5-242

Haire, R.N., Rast, J.P., Litman, R.T., and Litman, G.W. (2000) Characterization of three isotypes of immunoglobulin light chains and T-cell antigen receptor a in zebrafish. Immunogenetics. 51(11):915-923

Yoder, J.A., Haire, R.N., and Litman, G.W. (1999) Cloning of two zebrafish cDNAs that share domains with the MHC class II-associated invariant chain. Immunogenetics. 50:84-88

Icard-Liepkalns, C., Haire, R.N., Strong, S.J., and Litman, G.W. (1999) Cloning of a cDNA encoding a Pim1 homologue in zebrafish, Danio rerio. Immunogenetics. 49(4):351-353

Haire, R.N., Strong, S.J., and Litman, G.W. (1998) Tec-family non-receptor tyrosine kinase expressed in zebrafish kidney. Immunogenetics. 47:336-337

Amemiya, C., Ota, T., and Litman, G. (1996) Construction of P1 artificial chromosome (PAC) libraries from lower vertebrates. In Nonmammalian Genomic Analysis: A Practical Guide. B. Birren and E. Lai, eds. San Diego: Academic Press.