Brodmann (1909) area 4

Term ID

UBERON:0013535

Synonyms

• area 4 of Brodmann (guenon)
• area 4 of Brodmann-1909
• area gigantopyramidalis
• B09-4
• Brodmann (1909) area 4
• Brodmann area 4, gigantopyramidal

Definition

The term area 4 of Brodmann-1909 refers to a cytoarchitecturally defined portion of the frontal lobe of the guenon. It is located predominantly in the precentral gyrus. Brodmann-1909 regarded it as topographically and cytoarchitecturally homologous to the human gigantopyramidal area 4 and noted that it occupies a much greater fraction of the frontal lobe in the monkey than in the human. Distinctive features (Brodmann-1905): the cortex is unusually thick; the layers are not distinct; the cells are relatively sparsely distributed; giant pyramidal (Betz) cells are present in the internal pyramidal layer (V); lack of an internal granular layer (IV) such that the boundary between the external pyramidal layer (III) and the internal pyramidal layer (V) is indistinct; lack of a distinct external granular layer (II); a gradual transition from the multiform layer (VI) to the subcortical white matter.

References

• Brodmann_area:4
• UMLS:C1272526
• birnlex:1735
• http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=1014
• http://linkedlifedata.com/resource/umls/id/C1272526

Ontology

Uberon Ontology