inflammasome-mediated signaling pathway

Term ID

GO:0141084

Synonyms

inflammasome-mediated signal transduction

Definition

An intracellular signal transduction pathway that starts with a ligand binding to a pattern recognition receptor (PRR), assembly of the inflammasome complex, leading to the activation of CASP1 and inducing an inflammatory response. In some cases, inflammasome-mediated signal transduction can lead to programmed cell death, such as pyroptosis. 35883561

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is part of: inflammatory response

inflammatory response Show first 5 Terms
has parts: canonical inflammasome complex assembly

canonical inflammasome complex assembly Show first 5 Terms
is a type of: cytoplasmic pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway Show first 5 Terms
negatively regulated by: negative regulation of inflammasome-mediated signaling pathway

negative regulation of inflammasome-mediated signaling pathway Show first 5 Terms
positively regulated by: positive regulation of inflammasome-mediated signaling pathway

positive regulation of inflammasome-mediated signaling pathway Show first 5 Terms
regulated by: regulation of inflammasome-mediated signaling pathway

regulation of inflammasome-mediated signaling pathway Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations