very-long-chain 3-oxoacyl-CoA reductase activity

Term ID

GO:0141040

Synonyms

Definition

Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ = a very-long-chain 3-oxoacyl-CoA + H+ + NADPH. This reaction is the second (reduction) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit. (2)

References

• EC:1.1.1.330
• MetaCyc:RXN-7698
• RHEA:48680
• Reactome:R-HSA-548818

Ontology

GO: Molecular Function    QuickGO    AmiGO