HRI-mediated signaling

Term ID

GO:0140468

Synonyms

• EIF2AK1-mediated signaling

Definition

A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock. 27629041

References

Ontology

GO: Biological Process    QuickGO    AmiGO