double-strand break repair via classical nonhomologous end joining

Term ID

GO:0097680

Synonyms

• C-NHEJ
• canonical nonhomologous end joining

Definition

An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining). 18584027

References

Ontology

GO: Biological Process    QuickGO    AmiGO