perinucleolar compartment

Term ID

GO:0097356

Synonyms

• perinucleolar region

Definition

The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly enriched in this compartment. PTB and pol III transcripts are required for the integrity of the PNC. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO