cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Term ID

GO:0097199

Synonyms

activator caspase activity
apical caspase activity
cysteine-type endopeptidase activity involved in apoptotic signalling pathway
initiator caspase activity

Definition

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway. (2)

References

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is part of: apoptotic signaling pathway

apoptotic signaling pathway Show first 5 Terms
is a type of: cysteine-type endopeptidase activity cysteine-type endopeptidase activity involved in apoptotic process

cysteine-type endopeptidase activity cysteine-type endopeptidase activity involved in apoptotic process Show first 5 Terms
negatively regulated by: negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway Show first 5 Terms
positively regulated by: positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway Show first 5 Terms
regulated by: regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations