isotype switching to IgG isotypes

Term ID

GO:0048291

Synonyms

• class switching to IgG isotypes
• isotype switch recombination to IgG isotypes

Definition

The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus. (4)

References

Ontology

GO: Biological Process    QuickGO    AmiGO