Search Ontology:
GO: Cellular Component

oxoglutarate dehydrogenase complex

Term ID
GO:0045252
Synonyms
  • alpha-ketoglutarate dehydrogenase complex
  • dihydrolipoamide S-succinyltransferase complex
  • KGDHC
Definition
A multi-enzyme complex that catalyzes the oxidative decarboxylation of alpha-ketoglutarate (also known as 2-oxoglutarate) to form succinyl-CoA. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: oxoglutarate dehydrogenase (lipoamide) (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3). Additional proteins may also be present. 10672230
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes
Citations
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