retroviral integrase activity

Term ID

GO:0044823

Synonyms

Definition

Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism. 19091057

References

Ontology

GO: Molecular Function    QuickGO    AmiGO