endoplasmic reticulum quality control compartment

Term ID

GO:0044322

Synonyms

• ER quality control compartment
• ER-derived quality control compartment
• ERQC

Definition

A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins. 11408579

References

Ontology

GO: Cellular Component    QuickGO    AmiGO