calcitriol biosynthetic process from calciol

Term ID

GO:0036378

Synonyms

• 1alpha,25(OH)2D3 biosynthesis
• 1alpha,25-dihydroxycholecalciferol biosynthesis
• 1alpha,25-dihydroxyvitamin D3 biosynthesis
• calcitriol biosynthesis from calciol
• vitamin D3 activation

Definition

Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO