nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

Term ID

GO:0035872

Synonyms

• NLR signaling pathway
• NOD-like receptor signaling pathway
• nucleotide-binding domain leucine-rich repeat containing receptor signaling pathway
• nucleotide-binding domain, leucine rich repeat containing receptor signal transduction
• nucleotide-binding domain, leucine rich repeat containing receptor signal transduction pathway
• nucleotide-binding domain, leucine rich repeat containing receptor signalling pathway

Definition

The series of molecular signals initiated by a ligand binding to a nucleotide-binding domain, leucine rich repeat containing receptor (NLR), and ending with the regulation of a downstream cellular process. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. (3)

References

• Reactome:R-HSA-168643

Ontology

GO: Biological Process    QuickGO    AmiGO