interleukin-4-dependent isotype switching to IgE isotypes

Term ID

GO:0035708

Synonyms

• IL-4-dependent isotype switching to IgE isotypes

Definition

The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4). 12496423

References

Ontology

GO: Biological Process    QuickGO    AmiGO