24-hydroxycholesterol 7alpha-hydroxylase activity

Term ID

GO:0033782

Synonyms

• 24-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity
• 24-hydroxycholesterol 7alpha-monooxygenase activity

Definition

Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase]. (2)

References

• EC:1.14.14.26
• KEGG_REACTION:R07208
• MetaCyc:1.14.13.99-RXN
• RHEA:46124

Ontology

GO: Molecular Function    QuickGO    AmiGO