AP-1 adaptor complex

Term ID

GO:0030121

Synonyms

• AP-1 related adapter complex
• HA1
• HA1 clathrin adaptor

Definition

A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C). (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO