trypanothione biosynthetic process

Term ID

GO:0019342

Synonyms

trypanothione anabolism
trypanothione biosynthesis
trypanothione formation
trypanothione synthesis

Definition

The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress. 9677355

References

MetaCyc:TRYPANOSYN-PWY

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is a type of: glutathione derivative biosynthetic process trypanothione metabolic process

glutathione derivative biosynthetic process trypanothione metabolic process Show first 5 Terms
negatively regulated by: negative regulation of trypanothione biosynthetic process

negative regulation of trypanothione biosynthetic process Show first 5 Terms
positively regulated by: positive regulation of trypanothione biosynthetic process

positive regulation of trypanothione biosynthetic process Show first 5 Terms
regulated by: regulation of trypanothione biosynthetic process

regulation of trypanothione biosynthetic process Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations