JUN kinase kinase activity

Term ID

GO:0008545

Synonyms

• JNKK

Definition

Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase. (2)

References

• Reactome:R-HSA-168162

Ontology

GO: Molecular Function    QuickGO    AmiGO