metaphase/anaphase transition of mitotic cell cycle

Term ID

GO:0007091

Synonyms

metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
mitotic metaphase/anaphase transition

Definition

The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. 10465783

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is part of: mitotic cell cycle

mitotic cell cycle Show first 5 Terms
is a type of: metaphase/anaphase transition of cell cycle mitotic cell cycle phase transition

metaphase/anaphase transition of cell cycle mitotic cell cycle phase transition Show first 5 Terms
negatively regulated by: negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic metaphase/anaphase transition Show first 5 Terms
positively regulated by: positive regulation of mitotic metaphase/anaphase transition

positive regulation of mitotic metaphase/anaphase transition Show first 5 Terms
regulated by: regulation of mitotic metaphase/anaphase transition

regulation of mitotic metaphase/anaphase transition Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations