Search Ontology:
GO: Cellular Component

eukaryotic translation initiation factor 3 complex

Term ID
GO:0005852
Synonyms
  • eIF-3
  • eIF3
Definition
A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs. 15904532
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is part of
is a type of
has subtype
Phenotype
Phenotype caused by Genes
Citations
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