polypeptide N-acetylgalactosaminyltransferase activity

Term ID

GO:0004653

Synonyms

• glycoprotein acetylgalactosaminyltransferase activity
• polypeptide-N-acetylgalactosamine transferase activity
• protein-UDP acetylgalactosaminyltransferase activity
• UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity
• UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity
• UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity
• UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity
• UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity
• UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity
• UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity
• UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity
• UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity
• UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity
• UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity
• uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity

Definition

Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis. (2)

References

• EC:2.4.1.41
• MetaCyc:2.4.1.41-RXN
• Reactome:R-HSA-5096532
• Reactome:R-HSA-5096537
• Reactome:R-HSA-8851619
• Reactome:R-HSA-913675
• Reactome:R-HSA-9683760
• Reactome:R-HSA-9694438

Ontology

GO: Molecular Function    QuickGO    AmiGO