hydroxymethylglutaryl-CoA reductase (NADPH) activity

Term ID

GO:0004420

Synonyms

• 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity
• HMG-CoA reductase activity
• hydroxymethylglutaryl-CoA reductase activity

Definition

Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H+ + 2 NADPH. 29224355

References

• EC:1.1.1.34
• KEGG_REACTION:R02082
• MetaCyc:1.1.1.34-RXN
• RHEA:15989
• Reactome:R-HSA-191352

Ontology

GO: Molecular Function    QuickGO    AmiGO