T-helper 1 cell lineage commitment

Term ID

GO:0002296

Synonyms

• T-helper 1 cell fate commitment
• Th1 cell lineage commitment
• Th1 fate commitment

Definition

The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis. 0781735149

References

Ontology

GO: Biological Process    QuickGO    AmiGO