C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity

Term ID

GO:0000252

Synonyms

• 3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)
• 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)
• 3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)
• 3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity
• C-3 sterol dehydrogenase (C-4 decarboxylase) activity
• C-3 sterol dehydrogenase activity
• sterol 4alpha-carboxylic decarboxylase activity
• sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity
• sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

Definition

Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H. (2)

References

• EC:1.1.1.170
• Reactome:R-HSA-194642
• Reactome:R-HSA-194718

Ontology

GO: Molecular Function    QuickGO    AmiGO